Results 101 to 110 of about 167,144 (276)
Chemistry &Biodiversity, Accepted Article.Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali +11 more
wiley +1 more source
Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective [PDF]
, 2019 The melanocortin-4 receptor (MC4R) can be endogenously activated by binding of melanocyte-stimulating hormones (MSH), which mediates anorexigenic effects. In contrast, the agouti-related peptide (AgRP) acts as an endogenous inverse agonist and suppresses
Biebermann, Heike +10 more
core +1 more source
Synthetic Lignin Oligomers: Analytical Techniques, Challenges, and Opportunities
ChemSusChem, EarlyView.The review begins by discussing lignin and its structural complexity, followed by challenges in elucidating depolymerization products and the analytical techniques used. It then focuses on the chemical structure of synthetic lignin oligomers, their synthesis mechanisms, and their significance in current science. Finally, scientific gaps are identified,
Myriam Rojas +4 more
wiley +1 more source
Expresión diferencial de genes en Pyropia columbina (Bangiales, Rhodophyta) bajo hidratación y desecación natural [PDF]
, 2013 Indexación: Web of Science; Scielo.RESUMEN. En Zonas Costeras rocosas, la desecación es gatillada porción Cambios Diarios en los Niveles de marea, y la Evidencia indica experimental de Me Distribución de las algas en la zona intermareal no está ...
Contreras-Porcia, Loretto +10 more
core
G-Protein coupled receptor signalling in pluripotent stem cell-derived cardiovascular cells: Implications for disease modelling [PDF]
, 2015 Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths
Dolatshad, NF +4 more
core +1 more source
Simulations of Incompressible MHD Turbulence [PDF]
, 2000 We simulate incompressible MHD turbulence in the presence of a strong background magnetic field. Our major conclusions are: 1) MHD turbulence is most conveniently described in terms of counter propagating shear Alfven and slow waves. Shear Alfven waves control the cascade dynamics.
arxiv +1 more source
Enzymatic Treatment of Lignin in Alkaline Homogeneous Systems: A Review on Alkaliphilic Laccases
ChemSusChem, EarlyView.This review summarizes the enzymatic treatment of lignin in alkaline homogeneous systems, with a focus on alkaliphilic laccases. Unlike native laccases that promote lignin polymerization under acidic conditions, these enzymes work in basic pH, where industrial lignins are soluble.
Lou Delugeau +2 more
wiley +1 more source
Evolvability of Chaperonin Substrate Proteins [PDF]
, 2009 Molecular chaperones ensure that their substrate proteins reach the functional native state, and prevent their aggregation. Recently, an additional function was proposed for molecular chaperones: they serve as buffers (_capacitors_) for evolution by ...
Emanuele Raineri +3 more
core +1 more source
, 2004 Preliminary analysis of two selected genomic regions of Buchnera aphidicola BCc, the primary endosymbiont of the cedar aphid Cinara cedri, has revealed a number of interesting features when compared with the corresponding homologous regions of the three ...
Gil, Rosario +3 more
core +1 more source
Edinger-Westphal Nucleus [PDF]
, 2008 This report contains a summary of expression patterns for genes that are enriched in the Edinger-Westphal nucleus (EW) of the midbrain. All data are derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Allen Institute for Brain Science +3 more
core +2 more sources