Results 121 to 130 of about 71,714 (251)

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Sustainable Production of Peanut Protein Isolate: Optimization, Functional Characterization, and Comparison With Soy Protein

Sustainable Food Proteins, Volume 4, Issue 1, March 2026.
Process of obtaining peanut protein isolate from South American peanuts, highlighting extraction optimization and its potential as a sustainable functional food ingredient. ABSTRACT The agri‐food industry seeks sustainable and plant‐based protein sources that valorize industrial by‐products to meet the nutritional demands of the growing population and ...
Amadeo O. Martín Costa, Carla Aminahuel, Antonella Centomo, Ana Paula Vico, Yanina E. Rossi, Adriana N. Mauri, Mariana A. Montenegro   +6 more
wiley   +1 more source

Shade‐induced transcriptional reprogramming and metabolic adaptation in contrasting soybean genotypes

The Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Shade stress affects soybean yield in intercropping, but the molecular basis of cultivar‐specific tolerance is unclear. We analyzed shade‐tolerant (Guru) and sensitive (Heinong 53) soybeans under 30% and 70% shade using transcriptomic, physiological, and biochemical methods.
Fengyi Zhang, Runnan Zhou, Rongqiang Yuan, Xiao Zhu, Xinyue Zhang, Sobhi F. Lamlom, Dai Shi, Ahmed M. Abdelghany, Jidao Du, Honglei Ren, Lijuan Qiu   +10 more
wiley   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Genetic deficiency of the alpha subunit of the guanine nucleotide-binding protein Gs as the molecular basis for Albright hereditary osteodystrophy.

, 1988
Michael A. Levine, T G Ahn, Steven Klupt, Keith D. Kaufman, Philip M. Smallwood, Henry R. Bourne, Kathleen A. Sullivan, Cornelis Van Dop   +7 more
openalex   +2 more sources

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

, 1986
Hiroshi Itoh, Tohru Kozasa, Shigekazu Nagata, Shun Nakamura, Toshiaki Katada, M Ui, Shigenori Iwai, Eiko Ohtsuka, Hiroshi Kawasaki, Kazuyuki Suzuki   +9 more
openalex   +2 more sources

Deceptive beauty of non‐natural structures

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich, Eugenia V. Gurevich   +1 more
wiley   +1 more source

Optimized ACE2‐Fc fusion proteins with picomolar neutralization activity against highly evolved SARS‐CoV‐2 variants

Protein Science, Volume 35, Issue 2, February 2026.
Abstract The rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has compromised the efficacy of many authorized monoclonal antibody products. This highlights the need for alternative strategies, especially for vulnerable populations such as immunocompromised individuals.
Ferran Abancó, Ferran Tarrés‐Freixas, Rosalba Lepore, Elisa Molina‐Molina, Eloi Franco, Rytis Boreika, Edwards Pradenas, Dàlia Raïch‐Regué, Itziar Erkizia, Bonaventura Clotet, Alfonso Valencia, Júlia Vergara‐Alert, Joaquim Segalés, Jorge Carrillo, Nuria Izquierdo‐Useros, Julià Blanco, Benjamin Trinité   +16 more
wiley   +1 more source

Mutagenesis of the amino-terminal glycine to alanine in Gs alpha subunit alters beta gamma-dependent properties and decreases adenylylcyclase activation.

, 1993
Ronald van der Neut, C. Pantaloni, Isabelle Nebout, Joël Bockaert, Yves Audigier   +4 more
openalex   +1 more source