Results 121 to 130 of about 167,144 (276)
Altered response of adenylate cyclase to parathyroid hormone during compensatory renal growth [PDF]
Altered response of adenylate cyclase to parathyroid hormone during compensatory renal growth. The loss of renal mass is associated with functional adaptations in the remaining nephrons to maintain homeostasis.
Milanes, Carmen L.+5 more
core +1 more source
Corticotropin-releasing factor receptors couple to multiple g-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal excitability and associative learning [PDF]
Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the hippocampus.
Blank, T. (Thomas)+5 more
core +2 more sources
Abstract Selenium (Se) is essential for human and animal health and nutritional status. As humans cannot produce Se, it must be obtained from the diet. Adequate Se supplementation improves innate immunity, increases antioxidant capacity and helps prevent various disorders.
Muna Ali Abdalla+2 more
wiley +1 more source
Intracellular symbiosis is very common in the insect world. For the aphid Cinara cedri, we have identified by electron microscopy three symbiotic bacteria that can be characterized by their different sizes, morphologies, and electrodensities.
García-Verdugo, José Manuel+6 more
core +2 more sources
Recent Developments in the Optical Control of Adrenergic Signaling
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi+4 more
wiley +1 more source
SARS-CoV Regulates Immune Function-Related Gene Expressions in Human Monocytic Cells [PDF]
Background: Severe Acute Respiratory Syndrome (SARS) is characterized by acute respiratory distress (ARDS) and pulmonary fibrosis, and the monocyte/macrophage is the key player in the pathogenesis of SARS. Methods: In this study, we ...
Betty A. Wu-Hsieh+4 more
core +1 more source
Archimedean superrigidity of solvable S-arithmetic groups [PDF]
Let $\Ga$ be a connected, solvable linear algebraic group over a number field~$K$, let $S$ be a finite set of places of~$K$ that contains all the infinite places, and let $\theints$ be the ring of $S$-integers of~$K$. We define a certain closed subgroup~$\GOS$ of $\Ga_S = \prod_{v \in S} \Ga_{K_v}$ that contains $\Ga_{\theints}$, and prove that $\Ga_ ...
arxiv
ABSTRACT The condition of ancient marine ecosystems provides context for contemporary biodiversity changes in human‐impacted oceans. Sequencing sedimentary ancient DNA (sedaDNA) is an emerging method for generating high‐resolution biodiversity time‐series data, offering insights into past ecosystems.
Luke E. Holman+8 more
wiley +1 more source
Our study reveals that overactivation of both mTOR complexes through mLST8 in RPE cells triggers AMD‐like pathology and cellular dysfunction. This finding highlights the critical role of balanced mTOR signaling in retinal health and suggests that targeting both complexes could be therapeutic for AMD treatment.
Olivia Chowdhury+27 more
wiley +1 more source
Microscopy and spectroscopy approaches to study GPCR structure and function
Abstract The GPCR signalling cascade is a key pathway responsible for the signal transduction of a multitude of physical and chemical stimuli, including light, odorants, neurotransmitters and hormones. Understanding the structural and functional properties of the GPCR cascade requires direct observation of signalling processes in high spatial and ...
Tomáš Fessl+2 more
wiley +1 more source