Results 211 to 220 of about 71,714 (251)

Exclusion of close linkage of bipolar disorder to the Gs-α subunit gene in nine Australian pedigrees

Journal of Affective Disorders, 1994
Growing evidence suggests that guanine nucleotide binding proteins (G proteins) may be involved in both the pathogenesis and treatment of bipolar affective disorder. Both overactive G proteins and increased levels of the alpha subunit of the stimulatory form (Gs-alpha) have been demonstrated in peripheral leucocytes of manic patients while an increase ...
F, Le, P, Mitchell, C, Vivero, B, Waters, J, Donald, L A, Selbie, J, Shine, P, Schofield   +7 more
openaire   +2 more sources

A unique mRNA species for the α subunit of GS is present in rat haploid germ cells

Biochemical and Biophysical Research Communications, 1990
The 1.9 kb mRNA encoding the alpha subunit of Gs observed in the somatic cells of the rat testis was not seen in the germ cells (pachytene spermatocytes and round spermatids) as revealed by Northern blot analysis. Interestingly, the cDNA probe for Gs alpha detected a mRNA of shorter chain length (0.9 kb) exclusively in the haploid germ cells (round and
T B, Haugen, E J, Paulssen, J O, Gordeladze, V, Hansson   +3 more
openaire   +2 more sources

Mutations in the gene encoding the alpha-subunit of the Gs protein in molar pregnancy.

Endocrine, 2000
Molar pregnancy is a gestational trophoblastic disease associated with a trophoblastic proliferation and a protein synthesis alteration. It is characterized by the presence of hydatiform moles, which are fluid-filled cysts derived from the chorionic villi of the placenta.
G, Garon, J G, LeHoux, P, Bessette
openaire   +1 more source

Chimeras of the Gs alpha subunit that had the NH2- or COOH-terminal sequence substituted for the corresponding region of the Gi alpha subunit constitutively activate adenylyl cyclase.

Society of General Physiologists series, 1990
L E, Heasley, N, Dhanasekaran, S K, Gupta, S, Osawa, G L, Johnson   +4 more
openaire   +2 more sources

Altered Gs alpha N-terminus affects Gs activity and interaction with the G beta gamma subunit complex in cell membranes but not in solution.

Cellular signalling, 1996
The stimulatory G protein (Gs) mediates activation of adenylylcyclase by a ligand-receptor complex. Gs is heterotrimeric (alpha beta gamma) and activation can be accomplished by dissociation of the alpha-subunit (Gs alpha) from the beta gamma-subunit complex (G beta gamma).
D R, Warner, S, Okuya, R V, Rebois
openaire   +1 more source

Differential immunohistochemical labeling of Gs, G(il) and 2, and G(o) alpha-subunits in rat forebrain.

Synapse (New York, N.Y.), 1997
The anatomical and morphological distribution of the G proteins G(o), G(i1) and 2, and Gs alpha-subunits in rat forebrain sections was determined using immunohistochemical techniques. Diffuse G(o) labeling occurred in the neuropil throughout the cortex, superficial layers of the entorhinal cortex, thalamus, several white matter fiber tracts, and ...
D Y, Okuhara, J M, Lee, S G, Beck, N A, Muma   +3 more
openaire   +1 more source

The Alpha Magnetic Spectrometer (AMS) on the international space station: Part II — Results from the first seven years

Physics Reports, 2021
Yi Jia
exaly  

Expression of α Subunit of Gs in Escherichia coli

2002
Shui-Zhong, Yan, Wei-Jen, Tang
openaire   +2 more sources

Analysis of EGF receptor interactions with the alpha subunit of the stimulatory GTP binding protein of adenylyl cyclase, Gs.

Methods in molecular biology (Clifton, N.J.), 2006
Besides stimulating the mitogen-activated protein kinase, phospholipase Cgamma, and phosphatidylinositol 3-kinase cascades, in certain tissues and cells such as the heart, partotid gland, and luteal cells, activation of the epidermal growth factor (EGF) receptor also stimulates second-messenger systems that involve the heterotrimeric G proteins.
Deepti, Chaturvedi, Francis, Edwin, Hui, Sun, Tarun B, Patel   +3 more
openaire   +1 more source

CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

Signal Transduction and Targeted Therapy, 2021
Liang Chen, You-Chun Wang, Chuan Qin
exaly