Results 21 to 30 of about 167,144 (276)
Journal of Biological Chemistry, 1994 Although G protein alpha subunits are known to regulate such cellular functions as growth and enzymatic activity, the ability of these proteins to regulate target gene expression has not yet been directly investigated. Transient expression in GH3 pituitary cells of a target rat prolactin promoter-chloramphenicol acetyltransferase construct, (-1957)PRL ...
Jiajun Tian, Jie Chen, C Bancroft
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Mutation of the Gs protein alpha subunit NH2 terminus relieves an attenuator function, resulting in constitutive adenylyl cyclase stimulation. [PDF]
Molecular and Cellular Biology, 1990 Shoji Osawa +6 more
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Calcitonin values in pseudohypoparathyroidism [PDF]
Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor", 2023 Pseudohypoparathyroidism type 1A is a rare endocrine disorder caused by GNAS mutation and the resulting hormone resistance at the receptor level, i.e. the activation of the intracellular pathway of the Gs alpha subunit is not possible.
Marković Bojan +6 more
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Frontiers in Plant Science, 2022 The culmination of conventional yield improving parameters has widened the margin between food demand and crop yield, leaving the potential yield productivity to be bridged by the manipulation of photosynthetic processes in plants.
Mohammad Jan Shamim +4 more
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Phenotypic continuum of NFU1‐related disorders
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022 Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov +45 more
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The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
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Frontiers in Veterinary Science, 2022 Rapid growth is one of the most important economic traits in broiler breeding programs. Identifying markers and genes for growth traits may not only benefit marker-assisted selection (MAS)/genomic selection (GS) but also provide important information for
Shouzhi Wang +20 more
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Quantum tunneling of three-spine solitons through excentric barriers [PDF]
Physics Letters A 2022; 448: 128319, 2022 Macromolecular protein complexes catalyze essential physiological processes that sustain life. Various interactions between protein subunits could increase the effective mass of certain peptide groups, thereby compartmentalizing protein $\alpha$-helices.
arxiv +1 more source
Exposure to an Extremely-Low-Frequency Magnetic Field Stimulates Adrenal Steroidogenesis via Inhibition of Phosphodiesterase Activity in a Mouse Adrenal Cell Line. [PDF]
PLoS ONE, 2016 Extremely low-frequency magnetic fields (ELF-MFs) are generated by power lines and household electrical devices. In the last several decades, some evidence has shown an association between ELF-MF exposure and depression and/or anxiety in epidemiological ...
Kazuyoshi Kitaoka +4 more
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JADES: Discovery of extremely high equivalent width Lyman-alpha emission from a faint galaxy within an ionized bubble at z=7.3 [PDF]
A&A 678, A68 (2023), 2023 We report the discovery of a remarkable Ly$\alpha$ emitting galaxy at z = 7.2782, JADES-GS-z7-LA, with EW$_0$(Ly$\alpha$) $= 388.0 \pm 88.8$\AA and UV magnitude -17.0. The spectroscopic redshift is confirmed via rest-frame optical lines [O II], H$\beta$ and [O III] in its JWST/NIRSpec Micro-Shutter Assembly (MSA) spectrum.
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