Results 51 to 60 of about 167,144 (276)
The D153del mutation in GNB3 gene causes tissue specific signalling patterns and an abnormal renal morphology in rge chickens [PDF]
, 2011 Background The GNB3 gene is expressed in cone but not rod photoreceptors of vertebrates, where it acts as the β transducin subunit in the colour visual transduction process. A naturally occurring mutation ‘D153del’ in the GNB3 gene causes the recessively
Ali, Manir +8 more
core +6 more sources
Environmental Toxicology, Volume 38, Issue 1, Page 225-242, January 2023., 2023 Abstract Per‐ and polyfluoroalkyl substances (PFAS), which include perfluorooctanoic acid (PFOA), heptafluorobutyric acid (HFBA), and perfluorotetradecanoic acid (PFTA), are commonly occurring organic pollutants. Exposure to PFAS affects the immune system, thyroid and kidney function, lipid metabolism, and insulin signaling and is also involved in the ...
Qi Qi +6 more
wiley +1 more source
FASEB BioAdvances, Volume 4, Issue 12, Page 758-774, December 2022., 2022 Abstract The β2AR is a prototypical G protein‐coupled receptor (GPCR) known to orchestrate different cellular responses by the stimulation of specific signaling pathways. The best‐established signaling pathways for the β2AR are the canonical Gs pathway and the alternative β arrestin 2 (βarr2) pathway.
Emilio Y. Lucero‐Garcia Rojas +4 more
wiley +1 more source
Syndrome Fahr: Neurologic manifestation of endocrine disease [PDF]
Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor", 2020 Syndrome Fahr is described as calcification of the basal ganglia and is a rare inherited or sporadic neurological disease with a prevalence of 1:1000000 (1). For the first time described in 1930 in the works of Dr.
Miletić Marija +5 more
doaj
Increase in Gs and cyclic AMP generation in HIT cells
Journal of Biological Chemistry, 1989 Cyclic AMP accumulation in response to forskolin, cholera toxin, or isoproterenol is dramatically increased in HIT T-15 cells, a clonal cell line of Syrian hamster pancreatic islet beta cells, as a function of passage number. Forskolin and cholera toxin elevate cyclic AMP levels 5- to 10-fold higher in later passages (87-100) than in earlier passages ...
Timothy F. Walseth +4 more
openaire +3 more sources
Bioinformatic analysis for structure and function of Glutamine synthetase(GS) [PDF]
arXiv, 2022 Objective: To predict structure and function of Glutamine synthetase (GS) from Pseudoalteromonas sp. by bioinformatics technology, and to provide a theoretical basis for further study. Methods: Open reading frame (ORF) of GS sequence from Pseudoalteromonas sp. was obtained by ORF finder and was translated into amino acid residue.
arxiv
Mangiferin: Analgesic properties in neuropathic pain, molecular docking and meta-analysis
Phytomedicine Plus, 2022 Aim: : To investigate the analgesic effects of mangiferin (MAF) in experimental neuropathic pain (NPP) models and underlying mechanism. Methods: : Databases including Pubmed, Web of Science, Embase, Cochrane Library, China national knowledge ...
Bo-tao Chang +8 more
doaj
A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes [PDF]
, 1995 In many tissues, inwardly rectifying K channels are coupled to seven- helix receptors via the Gi/Go family of heterotrimeric G proteins. This activation proceeds at least partially via G beta gamma subunits.
Dascal, Nathan +4 more
core +2 more sources
Milky Way's eccentric constituents with $Gaia$, APOGEE $\&$ GALAH [PDF]
, 2022 We report the results of an unsupervised decomposition of the local stellar halo in the chemo-dynamical space spanned by the abundance measurements from APOGEE DR17 and GALAH DR3. In our Gaussian Mixture Model, only four independent components dominate the halo in the Solar neighborhood, three previously known $Aurora$, $Splash$ and Gaia-Sausage ...
arxiv +1 more source
Decoupled phase of frustrated spin-1/2 antiferromagnetic chains with and without long range order in the ground state [PDF]
, 2013 The quantum phases of one-dimensional spin $s= 1/2$ chains are discussed for models with two parameters, frustrating exchange $g = J_2 > 0$ between second neighbors and normalized nonfrustrating power-law exchange with exponent $\alpha$ and distance dependence $r^{-\alpha}$.
arxiv +1 more source