Results 251 to 260 of about 6,248 (265)

Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate

Cell Death and Disease, 2020
Xueran Chen, Zhiyou Fang, Haiming Dai
exaly  

Nanoagonist‐Mediated GSDME‐Dependent Pyroptosis Remodels the Inflammatory Microenvironment for Tumor Photoimmunotherapy

Advanced Functional Materials, 2023
Dawei Zhang
exaly  

Metformin activates AMPK/SIRT1/NF-κB pathway and induces mitochondrial dysfunction to drive caspase3/GSDME-mediated cancer cell pyroptosis

Cell Cycle, 2020
Guorong Li
exaly  

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

Cell Death and Disease, 2019
Junhui Yu, Xuejun Sun, Jianbao Zheng
exaly  

Procyanidin B2 Mitigates Methotrexate-Induced Hepatic Pyroptosis by Suppressing TLR4/NF-κB and Caspase-3/GSDME Pathways.

Food and Chemical Toxicology
J. Alsaab, W. Sarawi, Ahlam M. Alhusaini, I. Hasan, Sumayya A. Alturaif, Rehab A. Ali, Nouf M Alrasheed, Raeesa A. Mohammad, Norah K. Algarzae   +8 more
semanticscholar   +1 more source

Mitochondria-targeted H2O2 homeostatic disruptors: Harnessing glutathione autoxidation and reversing GSDME “silencing” for ferroptotic and dual-pathway pyroptotic oncotherapy

Nano Today
Junrong Wang, Yulin Xie, G. Zhu, Man Wang, Yanrong Qian, Qianqian Sun, Chunxia Li   +6 more
semanticscholar   +1 more source

Chemotherapeutic paclitaxel and cisplatin differentially induce pyroptosis in A549 lung cancer cells via caspase-3/GSDME activation

Apoptosis: an International Journal on Programmed Cell Death, 2019
Xian-Hui He, Bo Hu, Dong-Yun Ouyang
exaly  

GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver

Cell Death and Differentiation
Jia-Hui Zhu, Shen-Xi Ouyang, Guo-yan Zhang, Qi Cao, Ru-juan Xin, Hang Yin, Jing-Wen Wu, Yan Zhang, Zhen Zhang, Yi Liu, Jiang-Tao Fu, Yi-Ting Chen, Jie Tong, Jia-Bao Zhang, Jian Liu, Fu-Ming Shen, Dong-Jie Li, Pei Wang   +17 more
semanticscholar   +1 more source

Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells

Cell Death and Disease, 2020
Wei Han
exaly  

CircPDIA3/miR-449a/XBP1 feedback loop curbs pyroptosis by inhibiting palmitoylation of the GSDME-C domain to induce chemoresistance of colorectal cancer.

Drug resistance updates
Jiatong Lin, Zejian Lyu, Huolun Feng, Huajie Xie, Jingwen Peng, Weifu Zhang, Jun Zheng, Jiabin Zheng, Zihao Pan, Yong Li   +9 more
semanticscholar   +1 more source