Results 101 to 110 of about 273,251 (302)
Hematology, Transfusion and Cell TherapyObjetivo: Descrever as principais reações transfusionais imediatas e tardias ocorridas em hospitais atendidos pelo Grupo GSH no país. Material e métodos: O levantamento dos dados, foi realizado pelas informações obtidas do sistema informatizado do Grupo ...
RA Bento +7 more
doaj +1 more source
Effects of inhibiting antioxidant pathways on cellular hydrogen sulfide and polysulfide metabolism [PDF]
, 2019 Elaborate antioxidant pathways have evolved to minimize the threat of excessive reactive oxygen species (ROS) and to regulate ROS as signaling entities.
Gao, Yan, Olson, Kenneth R.
core +1 more source
Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy
Advanced Science, EarlyView.A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann +15 more
wiley +1 more source
Hematology, Transfusion and Cell TherapyObjetivo: Analisar a incidência de aloimunização em pacientes internados nos hospitais das agências transfusionais do país atendidas pela Grupo GSH. Material e métodos: Estudo retrospectivo realizado através do levantamento de dados obtidos do sistema ...
KJD Olio +7 more
doaj +1 more source
The effect of glutathione on human nuclear chromatin decondensation [PDF]
Introduction: During spermiogendsis, sperm chromatin histones are replaced by protamine. After fertilization, the sprem nucleus is decondenced by glutathione (GSH).
رضازاده ولوجردی, مجتبی +2 more
core
Advanced Science, EarlyView.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
Hematology, Transfusion and Cell TherapyIntrodução: Frequentemente, como relatado em literatura e visto na prática, há um excesso de pedidos de reserva de hemocomponentes em cirurgias eletivas, o que extrapola as necessidades reais, gerando desnecessariamente sobrecarga nos serviços de banco ...
EAF Oliveira +4 more
doaj +1 more source
The Galactic Distribution of Large HI Shells
, 2002 We report the discovery of nineteen new HI shells in the Southern Galactic Plane Survey (SGPS). These shells, which range in radius from 40 pc to 1 kpc, were found in the low resolution Parkes portion of the SGPS dataset, covering Galactic longitudes l ...
A. J. Green +17 more
core +1 more source
Advanced Science, EarlyView.This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu +7 more
wiley +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
Advanced Science, EarlyView.We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source