Results 301 to 310 of about 360,657 (334)
Some of the next articles are maybe not open access.
GSH transporters: molecular characterization and role in GSH homeostasis.
Biological chemistry Hoppe-Seyler, 1996Considerable progress has been made in the last few years in the molecular identification and characterization of hepatic GSH transporter-associated polypeptides. We are now poised to determine their precise mechanisms of action and regulation at the transcriptional and post-translational level. It is also anticipated that molecular characterization of
N, Kaplowitz +5 more
openaire +1 more source
2010
Loss of dopaminergic neurons, oxidative stress, deficient bioenergetics and decreased levels of reduced glutathione (GSH) in the substantia nigra are biochemical hallmarks of idiopathic Parkinson’s disease (PD). The intent of this study was to test the hypothesis that disturbances in GSH and dopamine (DA) homeostasis are detrimental to dopaminergic ...
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Loss of dopaminergic neurons, oxidative stress, deficient bioenergetics and decreased levels of reduced glutathione (GSH) in the substantia nigra are biochemical hallmarks of idiopathic Parkinson’s disease (PD). The intent of this study was to test the hypothesis that disturbances in GSH and dopamine (DA) homeostasis are detrimental to dopaminergic ...
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1,3-Dinitrobenzene Metabolism and GSH Depletion
Chemical Research in Toxicology, 2002Previous work demonstrated that the mitochondrial fraction of rat seminiferous tubules is capable of metabolizing 1,3-dinitrobenzene, using NADPH as a cofactor. Moreover, 1,3-dinitrobenzene treatment of rat tubules caused a decrease in mitochondrial GSH levels.
Ian T, Reeve +2 more
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The Leading Edge, 2013
Organizers of geoscience meetings have a difficult job because choosing a specific, narrow topic important to the petroleum industry, specifically to the E&P portion of the petroleum industry, is not a trivial task. What interests some may not interest others. Co-organizers argue in favor of one topic and then another.
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Organizers of geoscience meetings have a difficult job because choosing a specific, narrow topic important to the petroleum industry, specifically to the E&P portion of the petroleum industry, is not a trivial task. What interests some may not interest others. Co-organizers argue in favor of one topic and then another.
openaire +1 more source
Uptake of dehydroascorbic acid in high-GSH and normal-GSH dog erythrocytes
Comparative Clinical Pathology, 2005Uptake of dehydroascorbic acid (DHA) was studied in two types of dog erythrocytes with high GSH and normal GSH levels. Compared with ascorbic acid uptake, DHA produced a much greater ascorbic acid accumulation in dog erythrocytes. Both dog erythrocytes showed a concentration dependence of DHA uptake, and cellular ascorbic acid concentrations were ...
Eri Ogawa +3 more
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Potentiating photodynamic therapy of ICG-loaded nanoparticles by depleting GSH with PEITC.
Nanoscale, 2019Photodynamic therapy (PDT) is a clinically approved cancer treatment which utilizes reactive oxygen species (ROS) to eradicate cancer cells. But the high concentration of GSH inside tumor cells can neutralize the generated ROS during PDT, resulting in an
Hang Hu +13 more
semanticscholar +1 more source
ACS Applied Materials and Interfaces, 2019
An effective steady-state redox balance is maintained in cancer cells, allowing for protection against oxidative stress and thereby enhancing cell proliferation and tumor growth. Disruption of this redox balance would increase cellular content of ROS and
Longfa Kou +9 more
semanticscholar +1 more source
An effective steady-state redox balance is maintained in cancer cells, allowing for protection against oxidative stress and thereby enhancing cell proliferation and tumor growth. Disruption of this redox balance would increase cellular content of ROS and
Longfa Kou +9 more
semanticscholar +1 more source
Neuroscience Letters, 2011
To test whether copper exposure affects astroglial glutathione (GSH) metabolism, we have exposed astrocyte-rich primary cultures with copper chloride in concentrations of up to 30 μM and investigated cellular and extracellular GSH contents. Cultured astrocytes accumulated copper in a concentration-dependent manner thereby increasing the specific ...
Ivo F, Scheiber, Ralf, Dringen
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To test whether copper exposure affects astroglial glutathione (GSH) metabolism, we have exposed astrocyte-rich primary cultures with copper chloride in concentrations of up to 30 μM and investigated cellular and extracellular GSH contents. Cultured astrocytes accumulated copper in a concentration-dependent manner thereby increasing the specific ...
Ivo F, Scheiber, Ralf, Dringen
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GSH-Activatable NIR Nanoplatform with Mitochondria Targeting for Enhancing Tumor-Specific Therapy.
ACS Applied Materials and Interfaces, 2019Developing smart photosensitizers that are sensitive to tumor-specific signals for minimal side effects and enhanced antitumor efficacy is a tremendous challenge for tumor phototherapies.
Guoliang Yang +8 more
semanticscholar +1 more source
Archives of Pediatrics & Adolescent Medicine, 1968
To the Editor .—The comments by Drs. Di Toro, Ansanelli, and Lupi are most pertinent and interesting. They complement and confirm our results and we would like to express our appreciation for their comments The effects of other pharmacologic agents on sulfobromophthalein (BSP) metabolism should be interpreted with some caution because the effect may ...
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To the Editor .—The comments by Drs. Di Toro, Ansanelli, and Lupi are most pertinent and interesting. They complement and confirm our results and we would like to express our appreciation for their comments The effects of other pharmacologic agents on sulfobromophthalein (BSP) metabolism should be interpreted with some caution because the effect may ...
openaire +1 more source