Results 91 to 100 of about 3,474 (185)

Palaeoenvironmental and climatic changes from the lateglacial of the Saalian to the Late Weichselian in central Poland: a multiproxy study from Józefów

Boreas, EarlyView.
Józefów site is a case study which provides a detailed record of environmental and climate changes and confirms the main traces of the landscape morphogenesis of the Late Pleistocene established in central‐eastern Europe. This study presents a multiproxy reconstruction of palaeoenvironment under variable climatic conditions from the retreat of the ...
Aleksandra Majecka, Jacek Forysiak, Ryszard Borówka, Andreas Börner, Łukasz Bujak, Leszek Marks, Radosław Mieszkowski, Piotr Moska, Daniel Okupny, Małgorzata Pisarska‐Jamroży, Renata Stachowicz‐Rybka, Krzysztof Stachowicz   +11 more
wiley   +1 more source

Experimental and computational characterisation of the secondary fragment field in clinical proton therapy beams using microdosimetry

Precision Radiation Oncology, EarlyView.
Gabriele Parisi, Marta Missiaggia, Enrico Pierobon, Francesco Cordoni, Enrico Verroi, Claudio Verona, Giuseppe Schettino, Chiara La Tessa   +7 more
wiley   +1 more source

CKLF‐like MARVEL transmembrane domain‐containing superfamily 8 (CMTM8) promotes Notch signalling to maintain CD8+ T cell‐ and NK cell‐dependent tumour immune escape

British Journal of Pharmacology, EarlyView.
Background and Purpose The CKLF‐like MARVEL transmembrane domain containing superfamily (CMTM) has an important role in tumour immunity. The role of CMTM8 in tumour immune microenvironment (TIME) remains unknown. The aim was to investigate the relationship between CMTM8 and antitumour immunity. Experimental Approach Lentiviral system was established to
Fanglin Li, Longhua Gu, Runqiu Chen, Zhiying Li, Rong Zhang, Chen Chen, Yi Liu, Xinhang Zheng, Yiting Wang, Shanna Wu, Jianhua Sun, Jing Chen, Bingshun Wang, Likun Gong, Yiru Long   +14 more
wiley   +1 more source

High-Precision Experiments with Trapped Radioactive Ions Produced at Relativistic Energies

Atoms
Research on radioactive ion beams produced with in-flight separation of relativistic beams has advanced significantly over the past decades, with contributions to nuclear physics, nuclear astrophysics, atomic physics, and other fields.
Timo Dickel, Wolfgang R. Plaß, Emma Haettner, Christine Hornung, Sivaji Purushothaman, Christoph Scheidenberger, Helmut Weick   +6 more
doaj   +1 more source

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

The FEBS Journal, EarlyView.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang, Somaieh Ahmadian, Jolanda Piepers, Florian Bock, Tom Keulers, Marc A. Vooijs   +5 more
wiley   +1 more source

Length‐Based Spawning Potential Ratio Assessment of Key Species From a Remote Recreational Fishery at Diego Garcia, Indian Ocean

Fisheries Management and Ecology, EarlyView.
ABSTRACT Recreational fisheries in remote regions often operate under limited regulation and data availability, presenting challenges for sustainable management. Diego Garcia, located within the Chagos Marine Protected Area, hosts a unique recreational reef fishery embedded within a highly protected environment. We assessed the stock status of five key
Andrea N. Odell, David J. Curnick, Ronan C. Roche, Claire Collins, Kathryn E. Dawson, Ka'ohinani Kawahigashi, Chloe Le Blond, Andrew McInnis, Anna Patel, Sivajyodee Sannassy Pilly, Isobel Strudwick, Ami Vice, Brett M. Taylor   +12 more
wiley   +1 more source

Neuregulin 4‐dependent MAPK amplification mediates urate‐induced β‐cell dysfunction

Journal of Diabetes Investigation, EarlyView.
Hyperuricemia impairs glucose homeostasis by inducing pancreatic β‐cell apoptosis without insulin resistance. In male Uox‐KO mice, urate upregulates Nrg4, which amplifies MAPK signaling and drives β‐cell death. Thus, hyperuricemia disrupts glucose metabolism via the Nrg4‐MAPK axis.
Yunyang Wang, Kun Zhang, Zhiyuan Li, Shuhui Hu, Yiru Zhang, Yulei Zhao, Xiaohan Liu, Jie Lu   +7 more
wiley   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

Journal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez, Kristine F. Staveland, Mitchell S. Fleming, Pablo Balseiro, Cindy Pedrosa, Sigurd O. Handeland   +5 more
wiley   +1 more source

A single nucleotide polymorphism genotyping panel for efficient genetic stock identification of the Teno river Atlantic salmon (Salmo salar) population complex

Journal of Fish Biology, EarlyView.
Abstract A new single nucleotide polymorphism (SNP) panel for genetic stock identification in the Teno river Atlantic salmon, Salmo salar L., fishery was developed, with a view to improving on an existing microsatellite panel. Twenty‐two genetically differentiated reporting units were proposed based on population genetic analyses of 1212 individuals ...
Helena Johansson, Jaakko Erkinaro, Morten Falkegård, Anders Foldvik, Panu Orell, Craig R. Primmer, Victoria L. Pritchard   +6 more
wiley   +1 more source

Author Correction: Radon progeny measurements in a ventilated filter system to study respiratory-supported exposure

Scientific Reports, 2023
Franziska Papenfuß, Andreas Maier, Sonja Sternkopf, Claudia Fournier, Gerhard Kraft, Thomas Friedrich   +5 more
doaj   +1 more source