Results 101 to 110 of about 18,690 (260)

Author Correction: Radon progeny measurements in a ventilated filter system to study respiratory-supported exposure

open access: yesScientific Reports, 2023
Franziska Papenfuß   +5 more
doaj   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond   +6 more
wiley   +1 more source

Quantitative EUV ptychography reveals nanoscale morphological responses of bacteria under physiological and antibiotic stress

open access: yesPhotoniX
Table-top extreme ultraviolet (EUV) ptychography enables nanoscale, label-free, and quantitative imaging with intrinsic elemental sensitivity, offering a unique modality for subcellular profiling of bacterial morphology and composition.
Chang Liu   +9 more
doaj   +1 more source

Durability and Safety of Imeglimin as an Add‐On to DPP‐4 Inhibitors in Japanese Type 2 Diabetes: The 104‐Week FAMILIAR Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To evaluate the long‐term efficacy and safety of imeglimin added to dipeptidyl peptidase‐4 (DPP‐4) inhibitors in Japanese patients with type 2 diabetes, focusing on glycemic durability and safety in elderly patients over 104 weeks. Materials and Methods This multicenter, randomized, placebo‐controlled trial comprised a 24‐week double ...
Masashi Shimoda   +4 more
wiley   +1 more source

Systematic Comparison of High‐Fat Diet– and Streptozotocin‐Induced Prediabetic Obese C57BL/6J Mouse Models: A Sex‐Based Protocol Optimization Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Animal models of prediabetes (Pre‐DM) are essential for studying metabolic disease and testing therapies, yet high‐fat diet (HFD) and HFD‐plus‐streptozotocin (STZ) protocols vary in feeding duration, STZ dose, and diagnostic criteria and rarely account for sex.
Min Xu   +7 more
wiley   +1 more source

Disruption of iron metabolism resulting from Dmt1/Slc11a2 deficiency compromises Notch protein degradation and transcriptional activation

open access: yesThe FEBS Journal, EarlyView.
Divalent metal transporter 1 (Dmt1) maintains iron homeostasis and lysosomal proteostasis required for physiological Notch receptor–ligand signaling. Dmt1 loss lowers iron storage capacity (ferritin), increasing intracellular Fe2+, driving ROS and lipid peroxidation, and leading to lysosomal/mitochondrial dysfunction.
Rui Zhang   +5 more
wiley   +1 more source

Length‐Based Spawning Potential Ratio Assessment of Key Species From a Remote Recreational Fishery at Diego Garcia, Indian Ocean

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Recreational fisheries in remote regions often operate under limited regulation and data availability, presenting challenges for sustainable management. Diego Garcia, located within the Chagos Marine Protected Area, hosts a unique recreational reef fishery embedded within a highly protected environment. We assessed the stock status of five key
Andrea N. Odell   +12 more
wiley   +1 more source

Avoidance habit learning after recovery from anorexia nervosa: An fMRI study

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Anorexia Nervosa (AN) has been linked to altered self‐regulatory control processes and maladaptive habitual avoidance behavior. Both goal‐directed and habit systems may be relevant to AN, in which restrictive eating behavior can appear highly deliberate and increasingly automatic over time.
Clara M. Breier   +12 more
wiley   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

open access: yesJournal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez   +5 more
wiley   +1 more source

Studying of <i>Trachurus trachurus</i> (Linnaeus, 1758) Population Reproductive Dynamics in the Eastern Moroccan Mediterranean. [PDF]

open access: yesEcol Evol
Nasri H   +8 more
europepmc   +1 more source

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