Results 111 to 120 of about 106,875 (237)

P1057: INDIRECT TREATMENT COMPARISONS OF MOMELOTINIB VS PACRITINIB SAFETY AND ANEMIA OUTCOMES IN PATIENTS WITH MYELOFIBROSIS

HemaSphere, 2023
Lucia Masarova, Srdan Verstovsek, Francesca Palandri, Ruben Mesa, Claire Harrison, Balazs Dobi, Boris Gorsh, Zhaohui Wang, Catherine Ellis, Dwaipayan Patnaik, Venediktos Kapetanakis   +10 more
doaj   +1 more source

When You Come to a Fork in the Road, Take It: Wnt Signaling Activates Multiple Pathways through the APC/Axin/GSK-3 Complex. [PDF]

Cells, 2023
Li C, Furth EE, Rustgi AK, Klein PS.
europepmc   +1 more source

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

British Journal of Clinical Pharmacology, EarlyView.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung, Ju Hwan Kim, Da Eun Hyeon, Jeongmoon Ji, Min Young Lee, Hayun Choi, Dong Yun Lee, Min Woo Kim, Yoonmin Jang, Seonghoon Hwang, Jaehyeong Cho, Seok Young Song, Sang Youl Rhee, Jae Myung Cha, Won‐Woo Seo, Chang‐Won Jeong, Seung‐Jin Kwag, Woo Jin Kim, Jaeuk Hwang, Min‐ho Kim, Rae Woong Park, Ju‐Young Shin   +21 more
wiley   +1 more source

Naphthoquinone as a New Chemical Scaffold for Leishmanicidal Inhibitors of Leishmania GSK-3. [PDF]

Biomedicines, 2022
Sebastián-Pérez V, Martínez de Iturrate P, Nácher-Vázquez M, Nóvoa L, Pérez C, Campillo NE, Gil C, Rivas L.   +7 more
europepmc   +1 more source

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola, Aleksandar Gigov, Hubertus G. M. Leufkens, Andrew Bate, Marie Louise De Bruin, Helga Gardarsdottir   +5 more
wiley   +1 more source

In Silico Assessment of GSK-3? Inhibition Activity by Secondary Metabolites of Centella asiatica in the Development of Alzheimer’s Therapy

Journal of Tropical Pharmacy and Chemistry
Alzheimer’s disease involves excessive activity of glycogen synthase kinase-3? (GSK-3?), leading to tau hyperphosphorylation and neurofibrillary tangle formation.
Wiwin Azariani, Agus Dwi Ananto, Selvira Anandia Intan Maulidya   +2 more
doaj   +1 more source

Prospects in GSK-3 Signaling: From Cellular Regulation to Disease Therapy. [PDF]

Cells, 2022
Arciniegas Ruiz S, Rippin I, Eldar-Finkelman H.   +2 more
europepmc   +1 more source

Regulation of GSK-3 [PDF]

Cell, 2001
openaire   +1 more source

APOE genotype and the effect of statins on lipid outcomes: A meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim APOE genotype may affect statin therapy response. We conducted a meta‐analysis to update and quantify this association across various outcomes. Methods We searched seven databases (MEDLINE, Scopus, Web of Science, the Cochrane Library, APA PsycINFO, CINAHL Plus and ClinicalTrials.gov) on 9 May 2024.
Innocent G. Asiimwe, Tsegay Gebru, Andrea L. Jorgensen, Munir Pirmohamed, on behalf of the Multimorbidity Mechanism and Therapeutics Research Collaborative   +4 more
wiley   +1 more source

Small Molecule GSK-3 Inhibitors Safely Promote the Proliferation and Viability of Human Dental Pulp Stem Cells-In Vitro. [PDF]

Biomedicines, 2023
Hanna S, Aly R, Eldeen GN, Adanero Velasco A, Pérez Alfayate R.   +4 more
europepmc   +1 more source