Results 271 to 280 of about 16,343,665 (315)

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Avenanthramide A potentiates Bim-mediated antineoplastic properties of 5-fluorouracil via targeting KDM4C/MIR17HG/GSK-3β negative feedback loop in colorectal cancer. [PDF]

Acta Pharm Sin B
Fu R, Dou Z, Li N, Fan X, Amin S, Zhang J, Wang Y, Li Z, Li Z, Yang P.   +9 more
europepmc   +1 more source

Correction: GSK-3 Activity Is Critical for the Orientation of the Cortical Microtubules and the Dorsoventral Axis Determination in Zebrafish Embryos

, 2012
Ming Shao, Yushuang Lin, Zhongzhen Liu, Ying Zhang, Lifeng Wang, Changbin Liu, Hongwei Zhang   +6 more
openalex   +2 more sources

Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth

Oncogene, 2014
I. Azoulay-Alfaguter, R. Elya, L. Avrahami, A. Katz, H. Eldar-Finkelman   +4 more
semanticscholar   +1 more source

Gut microbiota and tuberculosis

iMeta, EarlyView.
This review explores the intricate relationship between gut microbiota (GM) and tuberculosis (TB). The figure illustrates the bidirectional effects between GM dynamics and TB progression, as well as the interactions between the GM and antituberculosis drugs.
Yanhua Liu, Ling Yang, Maryam Meskini, Anjana Goel, Monique Opperman, Sagar Singh Shyamal, Ajay Manaithiya, Meng Xiao, Ruizi Ni, Yajing An, Mingming Zhang, Yuan Tian, Shuang Zhou, Zhaoyang Ye, Li Zhuang, Linsheng Li, Istuti Saraswat, Ankita Kar, Syed Luqman Ali, Shakir Ullah, Syed Yasir Ali, Shradha Kaushik, Tianmu Tian, Mingyang Jiao, Shujun Wang, Giulia Ghisleni, Alice Armanni, Sara Fumagalli, WenYu Wang, Chao Cao, Maria Carpena, Miguel A. Prieto, Antonia Bruno, Chanyuan Jin, Hanqing Hu, Yuhang Zhang, Ilse du Preez, Ashok Aspatwar, Lingxia Zhang, Wenping Gong   +39 more
wiley   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

A longitudinal study of psychological distress during and after COVID‐19 restrictions in caregivers of children with intellectual disability in the UK

JCPP Advances, EarlyView.
Abstract Introduction The current study explored longitudinally whether child behaviours that challenge and caregiver coping strategies was associated with psychological distress in caregivers of children with and without intellectual disability during and after lockdown.
Karri Gillespie‐Smith, Karen Goodall, Doug McConachie, Jo Van Herwegen, Hayley Crawford, Carrie Ballantyne, Caroline Richards, Thomas Gallagher‐Mitchell, Joanna Moss, Grace Khawam, Laura Outhwaite, Emily Marriott, Freyja Steindorsdottir, Hope Christie   +13 more
wiley   +1 more source

The role of artificial intelligence in pharmacy: Revolutionizing drug development and beyond

Journal of Intelligent Medicine, EarlyView.
This comprehensive review explores the integration of artificial intelligence (AI) in the field of pharmacy, covering advancements in drug discovery, personalized medicine, medication management, and patient care. It synthesizes current research, methodologies, and future prospects, offering insights into how AI technologies are reshaping ...
Usman Shettima Usman, Farogh Ahsan, Muhammad Alanjiro, Saidu Yahaya Bataba, Jibrin Abdullahi Dallatu, Tarique Mahmood, Shahzadi Bano, Jamal Akhtar Ansari, Saba Parveen   +8 more
wiley   +1 more source

Patient's Perspective on the Impact of Psoriasis on Their Quality of Life After 1 Year of Tildrakizumab Treatment: Despite Clinical Improvement, Persistence of a Potential Mental Cicatricial Memory of the Disease

JEADV Clinical Practice, EarlyView.
In this real‐life study, tildrakizumab confirmed its efficacy in treating moderate‐to‐severe psoriasis, including challenging areas. Despite good disease control, some patients expressed dissatisfaction, highlighting the cumulative mental burden of delayed effective treatment and underscoring the mental scars left by psoriasis, persisting even after ...
Ziad Reguiai, Pierre André Becherel, Jean Luc Perrot, Anne Claire Fougerousse, Edouard Begon, Claire Poreaux, Claire Boulard, Guillaume Chaby, Charlotte Fite, Inès Zaraa, Dominique Lons‐Danic, Anne‐Laure Liegeon, Josiane Parier, Nathalie Quiles‐Tsimaratos, Laure Mery‐Bossard, François Maccari, for the OMCCI Group   +16 more
wiley   +1 more source

Sun Exposure Behaviors of Patients With Moderate‐to‐Severe Psoriasis: Results From the French PSOBIOTEQ Cohort

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Tanning addiction is a behavioral addiction characterized by an irrepressible desire for sun or ultraviolet light exposure. It is thought to affect 10% to 25% of the population. Objectives This study aimed to estimate the prevalence of this behavior in patients with moderate‐to‐severe psoriasis and identify associated factors ...
E. Mahé, R. Curmin, C. Paul, H. Bachelez, M. Beylot‐Barry, N. Beneton, A. Dupuy, P. Joly, D. Jullien, M.‐A. Richard, M. Viguier, E. Sbidian, O. Chosidow, F. Tubach, the PsoBioTeq Study group   +14 more
wiley   +1 more source