Results 71 to 80 of about 16,343,665 (315)
Advanced Materials, EarlyView.This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang +3 more
wiley +1 more source
The GSK-3 family as therapeutic target for myocardial diseases.
Circulation Research, 2015 Glycogen synthase kinase-3 (GSK-3) is one of the few signaling molecules that regulate a truly astonishing number of critical intracellular signaling pathways. It has been implicated in several diseases including heart failure, bipolar disorder, diabetes
Hind Lal +3 more
semanticscholar +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
GSK-3 Inhibitors and Tooth Repair: An Ethical Analysis [PDF]
Frontiers in Pharmacology, 2019 Tideglusib®, a GSK-3 inhibitor, was initially tested for the treatment of Alzheimer's disease. However, a recent report has suggested its potential off-label use for the treatment of dental cavities. Even if this effect is not yet confirmed, this off-label use can have significant public/dental health consequences, mainly because of the large number of
Catalin Dogaroiu +4 more
openaire +3 more sources
Biology Direct, 2011 Background Glycogen synthase kinase-3 (GSK-3) is a ubiquitously expressed serine/threonine (Ser/Thr) kinase comprising two isoforms, GSK-3α and GSK-3β. Both enzymes are similarly inactivated by serine phosphorylation (GSK-3α at Ser21 and GSK-3β at Ser9 ...
Kypta Robert M, Campa Victor M
doaj +1 more source
Tissue-specific analysis of glycogen synthase kinase-3α (GSK-3α) in glucose metabolism: effect of strain variation. [PDF]
PLoS ONE, 2011 Over-activity and elevated expression of glycogen synthase kinase-3 (GSK-3) has been implicated in the etiology of insulin resistance and Type 2 diabetes.
Satish Patel +2 more
doaj +1 more source
Advanced Optical Materials, EarlyView.This work presents a cost effective and sustainable approach of designing flexible, water resistant and bright green luminescent Y3Al5O12:Er3+/Yb3+ upconversion nanoparticles (UCNPs) incorporated into cellulose paper for anti‐counterfeiting and volatile organic compounds (VOCs) detection applications.
Annu Balhara +5 more
wiley +1 more source
Inhibition of GSK-3 ameliorates the pathogenesis of Huntington's disease
Neurobiology of Disease, 2021 In Huntington's disease (HD), the mutant huntingtin (mHtt) accumulates as toxic aggregates in the striatum tissue, with deleterious effects on motor-coordination and cognitive functions. Reducing the levels of mHtt is therefore a promising therapeutic strategy.
Amar Sarsor +5 more
openaire +4 more sources
Novel reporter alleles of GSK-3α and GSK-3β.
PLoS ONE, 2012 Glycogen Synthase Kinase 3 (GSK-3) is a key player in development, physiology and disease. Because of this, GSK-3 inhibitors are increasingly being explored for a variety of applications. In addition most analyses focus on GSK-3β and overlook the closely
William B Barrell +2 more
doaj +1 more source
eAmidation: An Electrochemical Amidation of Aldehydes via the Oxidation of N‐Aryl Hydrazones
Advanced Synthesis &Catalysis, EarlyView.The indirect electrochemical oxidation of N‐aryl hydrazones offers an efficient approach to access amides from aldehydes and amines. The AZADO‐mediated reaction enables the selective synthesis of a broad range of valuable amides using readily available aldehydes.
Luke Chen +2 more
wiley +1 more source