Results 41 to 50 of about 22,957 (191)

Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity

open access: yesAngewandte Chemie International Edition, EarlyView.
Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim   +10 more
wiley   +1 more source

Impact of Heated Versus Unheated Cooking Oil on Postprandial Vascular Function and Metabolism

open access: yesLipids, EarlyView.
ABSTRACT The impact of repeated heating of seed‐based culinary oils on cardiometabolic health has not been well established. Heating oils to high temperatures (> 150°C) causes lipid peroxidation, thus generating potentially harmful compounds that may impair vascular function. This randomized, single‐blind, crossover study investigated the acute effects
Rosiered Brownson‐Smith   +5 more
wiley   +1 more source

Nitric Oxide Is the Cause of Nitroglycerin Tolerance: Providing an Old Dog New Tricks for Acute Heart Failure

open access: yesJournal of Cardiovascular Pharmacology and Therapeutics, 2022
Our paper highlights the past 50 years of research focusing solely on tolerance involving nitroglycerin (glyceryl trinitrate, GTN). It also identifies and discusses inconsistencies in previous mechanistic explanations that have failed to provide a way to
Wayne Kaesemeyer MD   +1 more
doaj   +1 more source

Arithmetic of marked order polytopes, monotone triangle reciprocity, and partial colorings [PDF]

open access: yes, 2013
For a poset P, a subposet A, and an order preserving map F from A into the real numbers, the marked order polytope parametrizes the order preserving extensions of F to P.
Jochemko, Katharina, Sanyal, Raman
core  

Quasi maximum likelihood estimation and prediction in the compound Poisson ECOGARCH(1,1) model [PDF]

open access: yes, 2006
This paper deals with the problem of estimation and prediction in a compound Poisson ECOGARCH(1,1) model. For this we construct a quasi maximum likelihood estimator under the assumption that all jumps of the log-price process are observable.
Czado, Claudia, Haug, Stephan
core   +1 more source

Current Evidence on Immunotherapy for Gestational Trophoblastic Neoplasia (GTN)

open access: yesCancers, 2022
Background: Gestational trophoblastic disease includes a rare group of benign and malignant tumors derived from abnormal trophoblastic proliferation. Malignant forms are called gestational trophoblastic neoplasia (GTN) and include invasive mole, choriocarcinoma, placental site trophoblastic tumor and epithelioid trophoblastic tumor.
Mangili, Giorgia   +7 more
openaire   +2 more sources

School achievement in the Brazilian rural Amazon: An analysis of the interaction among motor, cognitive and environmental factors

open access: yesBritish Journal of Developmental Psychology, EarlyView.
Abstract A cross‐sectional study of 106 students (7–12 years) from a rural school in the Brazilian Amazon investigated the interaction among motor, cognitive and environmental factors on school achievement using network analysis. Students with good school performance were significantly older and showed superior global physical fitness, motor ...
Douglas Vieira   +3 more
wiley   +1 more source

P174 HEMODYNAMIC AND AUTONOMIC EFFECTS OF LOW-DOSE GLYCERYL TRINITRATE USED TO TEST ENDOTHELIUM-INDEPENDENT VASODILATION OF THE BRACHIAL ARTERY

open access: yesArtery Research, 2017
Background/Aim: Smooth muscle function is explored by sublingual glyceryl trinitrate (GTN) administration in vascular function protocols, in order to compare with endothelium- dependent vasodilation of the brachial artery by flow-mediated dilation (FMD).
Lorenzo Ghiadoni   +2 more
doaj   +1 more source

Supersymmetric Kaluza-Klein reductions of M-waves and MKK-monopoles [PDF]

open access: yes, 2002
We investigate the Kaluza-Klein reductions to ten dimensions of the purely gravitational half-BPS M-theory backgrounds: the M-wave and the Kaluza-Klein monopole.
Bryant R   +10 more
core   +2 more sources

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro   +14 more
wiley   +1 more source

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