Results 11 to 20 of about 374,227 (387)
The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability [PDF]
eLife, 2019 Microtubules are bistable cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage 1. Growing microtubules are thought to be stabilized by a GTP cap at their ends 2-5. The nature of this cap, however,
Johanna Roostalu +5 more
semanticscholar +6 more sources
GTP: Gatekeeper for Autophagy [PDF]
Molecular Cell, 2010 Chaperone-mediated autophagy (CMA) is involved in cellular quality control, and in the response to stress, deterioration in CMA contributes to the aging phenotype and to various disorders. The paper by Bandyopadhyay et al. in this issue of Molecular Cell demonstrates the role of GTP binding by elongation factor 1 alpha (EF1alpha) in regulating the ...
Isabelle Beau, Patrice Codogno
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Journal of Biological Chemistry, 2002 Because of the apparently greater conformational flexibility of yeast versus muscle actin and the ability of other members in the actin protein superfamily to efficiently use both ATP and GTP, we assessed the ability of yeast actin to function with GTP.
Xiaoyi Yao +2 more
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Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin
Biomolecules, 2022 Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South ...
Kiran S. Toti +4 more
doaj +1 more source
Kinetic analysis of GTP hydrolysis catalysed by the Arf1-GTP-ASAP1 complex [PDF]
Biochemical Journal, 2007 Arf (ADP-ribosylation factor) GAPs (GTPase-activating proteins) are enzymes that catalyse the hydrolysis of GTP bound to the small GTP-binding protein Arf. They have also been proposed to function as Arf effectors and oncogenes. We have set out to characterize the kinetics of the GAP-induced GTP hydrolysis using a truncated form of ASAP1 [Arf GAP with ...
Ruibai Luo +6 more
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Frontiers in Earth Science, 2022 Three dimensional (3D) geological model is frequently used to represent the geological conditions of the subsurface. The generalized triangular prism (GTP) model designed for borehole sampling data is a spatial data model that could retain the internal ...
Liming Sun +5 more
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RalA and RalB Function as the Critical GTP Sensors for GTP-Dependent Exocytosis [PDF]
The Journal of Neuroscience, 2007 Although it has been established that the activation of GTPases by non-hydrolyzable GTP stimulates neurotransmitter release from many different secretory cell types, the underlying mechanisms remain unclear. In the present study we aimed to elucidate the functional role(s) for endogenous Ras-like protein A (RalA) and RalB GTPases in GTP-dependent ...
Lakshmanan Arunachalam +10 more
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Frontiers in Psychology, 2022 Game Transfer Phenomena (GTP) refers to a cluster of involuntary phenomena related to playing videogames, including sensory and cognitive intrusions, transient changes in perception and self-agency.
Angelica B. Ortiz de Gortari +2 more
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GTP cyclohydrolase I utilizes metal‐free GTP as its substrate [PDF]
European Journal of Biochemistry, 2003 GTP cyclohydrolase I (GCH) is the rate‐limiting enzyme for the synthesis of tetrahydrobiopterin and its activity is important in the regulation of monoamine neurotransmitters such as dopamine, norepinephrine and serotonin. We have studied the action of divalent cations on the enzyme activity of purified recombinant human GCH expressed in Escherichia ...
T. Suzuki, H. Kurita, H. Ichinose
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Probiotic shelf life, antioxidant, sensory, physical and chemical properties of yogurts produced with lactobacillus acidophilus and green tea powder [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 The aim of the present study was to determine the effects of the addition of green tea powder (GTP) in the production of yogurt on survival of Lactobacillus acidophilus (P) and the yogurt properties. Four yogurt groups (yogurt without P and GTP, Control,
Songül ÇAKMAKÇI +7 more
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