Results 31 to 40 of about 187,197 (244)

Clinical Significance of Gamma-Glutamyltranspeptidase Combined with Carbohydrate-Deficient Transferrin for the Assessment of Excessive Alcohol Consumption in Patients with Alcoholic Cirrhosis

Medicines, 2021
Background: This study aimed to compare the diagnostic performance of carbohydrate-deficient transferrin (CDT) and gamma-glutamyltranspeptidase (γ-GTP) to assess the single and combined benefits of these biological markers for the detection of chronic ...
Akihiko Shibamoto, Tadashi Namisaki, Junya Suzuki, Takahiro Kubo, Satoshi Iwai, Fumimasa Tomooka, Soichi Takeda, Yuki Fujimoto, Masahide Enomoto, Koji Murata, Takashi Inoue, Koji Ishida, Hiroyuki Ogawa, Hirotetsu Takagi, Daisuke Kaya, Yuki Tsuji, Takahiro Ozutsumi, Yukihisa Fujinaga, Masanori Furukawa, Norihisa Nishimura, Yasuhiko Sawada, Koh Kitagawa, Shinya Sato, Hiroaki Takaya, Kosuke Kaji, Naotaka Shimozato, Hideto Kawaratani, Kei Moriya, Takemi Akahane, Akira Mitoro, Hitoshi Yoshiji   +30 more
doaj   +1 more source

GTP cyclohydrolase I utilizes metal‐free GTP as its substrate [PDF]

European Journal of Biochemistry, 2003
GTP cyclohydrolase I (GCH) is the rate‐limiting enzyme for the synthesis of tetrahydrobiopterin and its activity is important in the regulation of monoamine neurotransmitters such as dopamine, norepinephrine and serotonin. We have studied the action of divalent cations on the enzyme activity of purified recombinant human GCH expressed in Escherichia ...
T. Suzuki, H. Kurita, H. Ichinose
openaire   +2 more sources

In vitro and in vivo analyses of co-infections with peste des petits ruminants and capripox vaccine strains

Virology Journal, 2021
Background Peste des petits ruminants (PPR) and goat pox (GTP) are two devastating animal epidemic diseases that affect small ruminants. Vaccination is one of the most important measures to prevent and control these two severe infectious diseases ...
Dajun Zhang, Bo Yang, Ting Zhang, Xijuan Shi, Chaochao Shen, Haixue Zheng, Xiangtao Liu, Keshan Zhang   +7 more
doaj   +1 more source

Comprehensive Characterization of ^SGTP-Binding Proteins by Orthogonal Quantitative ^SGTP-Affinity Profiling and ^SGTP/GTP Competition Assays

Analytical Chemistry, 2014
Thiopurine drugs are widely used as antileukemic drugs and immunosuppressive agents, and 6-thioguanosine triphosphate ((S)GTP) is a major metabolite for these drugs. Recent studies have suggested that thiopurine drugs may exert their cytotoxic effects partly through binding of (S)GTP to a GTP-binding protein, Rac1.
Xiao, Yongsheng, Ji, Debin, Guo, Lei, Wang, Yinsheng   +3 more
openaire   +2 more sources

Green tea powder supplementation increased viscosity and decreased lysozyme activity of egg white during storage of eggs from Huainan partridge chicken

Italian Journal of Animal Science, 2020
The aim of this study was to evaluate whether green tea powder (GTP) addition could affect egg quality and egg storage. Eggs were collected after 12 weeks of feeding from control and GTP treatment groups of Huainan partridge hens.
Junzhi Zhang, Minghui Zhang, Weiwei Liang, Zhaoyu Geng, Xingyong Chen   +4 more
doaj   +1 more source

RalA and RalB Function as the Critical GTP Sensors for GTP-Dependent Exocytosis [PDF]

The Journal of Neuroscience, 2007
Although it has been established that the activation of GTPases by non-hydrolyzable GTP stimulates neurotransmitter release from many different secretory cell types, the underlying mechanisms remain unclear. In the present study we aimed to elucidate the functional role(s) for endogenous Ras-like protein A (RalA) and RalB GTPases in GTP-dependent ...
Gang, Li, Liping, Han, Ting-Chieh, Chou, Yoshihito, Fujita, Lakshmanan, Arunachalam, Ainan, Xu, Aaron, Wong, Soon-Kwang, Chiew, Qi, Wan, Li, Wang, Shuzo, Sugita   +10 more
openaire   +2 more sources

Essential role of GTP in epinephrine stimulation of human fat cell adenylate cyclase

Journal of Lipid Research, 1981
The activity of epinephrine-sensitive adenylate cyclase of human fat cell ghosts is markedly enhanced by the GTP analog 5'-guanylyl-imidodiphosphate (GMP-P(NH)P), but a similar effect of GTP itself has not been heretofore demonstrable.
M S Katz, J S Partilla, M A Piñeyro, R I Gregerman   +3 more
doaj   +1 more source

Water Cooking Stability of Dried Noodles Enriched with Different Particle Size and Concentration Green Tea Powders

Foods, 2020
Incorporating green tea powder (GTP) into dried noodles enriched the functional characteristics of noodles. To achieve the maximum benefits from GTP, the water cooking stability of dried green tea noodles (DGTN) should be investigated.
Kun Yu, Hui-Ming Zhou, Ke-Xue Zhu, Xiao-Na Guo, Wei Peng   +4 more
doaj   +1 more source

Dietary green tea powder supplementation enriched egg nutrients and physicochemical property in an indigenous chicken breed

Poultry Science, 2021
Dietary supplementation of green tea changes the antioxidative capacity of chickens. However, the effect of green tea supplementation in the diet on egg quality and the consequent change in processing capacity is still not well known.
Xingyong Chen, Tao Li, Kaiqin He, Zhaoyu Geng, Xiaochun Wan   +4 more
doaj   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source