Results 31 to 40 of about 339,556 (339)

Dynamics of Microtubule Growth and Catastrophe [PDF]

, 2007
We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii ...
Antal, T., Chakraborty, B., Krapivsky, P. L., Mailman, M., Redner, S.   +4 more
core   +1 more source

Interaction between chromium GTP and tubulin. Stereochemistry of GTP binding, GTP hydrolysis, and microtubule stabilization

Journal of Biological Chemistry, 1991
Chromium GTP (CrGTP) has been used to probe the stereochemistry of metal-GTP binding to exchangeable site of tubulin and to examine the fate and role of nucleotide-bound metal ion in GTP hydrolysis associated with microtubule assembly. The absolute stereoconfiguration of the two pairs of diastereomers of beta,gamma-bidentate CrGTP has been determined ...
M F, Carlier, D, Didry, C, Valentin-Ranc
openaire   +2 more sources

Regulation of local GTP availability controls RAC1 activity and cell invasion

Nature Communications, 2021
Changes in intracellular GTP levels are not considered as a regulatory event in RAC1 activation in live cells since total GTP levels are substantially higher than the RAC1 GTP dissociation constant determined in vitro.
Anna Bianchi-Smiraglia, David W. Wolff, Daniel J. Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M. Wombacher, Ashley L. Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O’Brien Cox, Cristina M. Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J. Sousa, Mikhail E. Kandel, Eugene S. Kandel, Klaus M. Hahn, Mikhail A. Nikiforov   +23 more
doaj   +1 more source

Spatiotemporal Variations and Convergence Characteristics of Green Technological Progress in China’s Mariculture

Fishes, 2023
The sustainability of mariculture depends on adopting green technologies, which can mitigate the negative impacts on the environment and ensure long-term viability.
Jianyue Ji, Nana Zhao, Jinglin Zhou, Chengjia Wang, Xia Zhang   +4 more
doaj   +1 more source

Analysis of GTP-binding potein function with a photoaffinity GTP analog.

Folia Pharmacologica Japonica, 1995
The mechanism whereby hormones or neurotransmitters activate G proteins and their intracellular effectors can be studied in reconstituted systems using purified components. However, the regulation of receptor-G protein signaling appears to be substantially more complex in the cell and several additional components participate in this event.
S, Hatta, H, Ohshika
openaire   +3 more sources

Effect of Dietary Japanese Green Tea Powder Supplementation on Feed Utilization and Carcass Profiles in Broilers

The Journal of Poultry Science, 2001
Responses of broiler to dietary Japanese green tea powder (GTP) were investigated using 30 broiler chicks reared from 18 to 52 days of age. Five rations were formulated by addition of 0, 0.5, 0.75, 1.0 and 1.5% of GTP to starter and finisher diets, and ...
Abdul Hai Biswas, Masaaki Wakita
doaj   +1 more source

Clinical Significance of Gamma-Glutamyltranspeptidase Combined with Carbohydrate-Deficient Transferrin for the Assessment of Excessive Alcohol Consumption in Patients with Alcoholic Cirrhosis

Medicines, 2021
Background: This study aimed to compare the diagnostic performance of carbohydrate-deficient transferrin (CDT) and gamma-glutamyltranspeptidase (γ-GTP) to assess the single and combined benefits of these biological markers for the detection of chronic ...
Akihiko Shibamoto, Tadashi Namisaki, Junya Suzuki, Takahiro Kubo, Satoshi Iwai, Fumimasa Tomooka, Soichi Takeda, Yuki Fujimoto, Masahide Enomoto, Koji Murata, Takashi Inoue, Koji Ishida, Hiroyuki Ogawa, Hirotetsu Takagi, Daisuke Kaya, Yuki Tsuji, Takahiro Ozutsumi, Yukihisa Fujinaga, Masanori Furukawa, Norihisa Nishimura, Yasuhiko Sawada, Koh Kitagawa, Shinya Sato, Hiroaki Takaya, Kosuke Kaji, Naotaka Shimozato, Hideto Kawaratani, Kei Moriya, Takemi Akahane, Akira Mitoro, Hitoshi Yoshiji   +30 more
doaj   +1 more source

GTP cyclohydrolase I utilizes metal‐free GTP as its substrate [PDF]

European Journal of Biochemistry, 2003
GTP cyclohydrolase I (GCH) is the rate‐limiting enzyme for the synthesis of tetrahydrobiopterin and its activity is important in the regulation of monoamine neurotransmitters such as dopamine, norepinephrine and serotonin. We have studied the action of divalent cations on the enzyme activity of purified recombinant human GCH expressed in Escherichia ...
T. Suzuki, H. Kurita, H. Ichinose
openaire   +2 more sources

Reciprocal regulation of PKA and rac signaling [PDF]

, 2013
Activated G protein-coupled receptors (GPCRs) and receptor tyrosine kinases relay extracellular signals through spatial and temporal controlled kinase and GTPase entities.
A. Riml, Baillie, Bhola, Birukova, Cook, Cuevas, Daaka, Delcourt, Dewire, Dorsam, Dumaz, E. Stefan, Eblen, G. S. Baillie, Gerits, Gloerich, Hafner, Hoffmann, Howe, Jaffe, K. R. Liedl, Kinderman, King, Kraynov, Kumar, Ligr, Malbon, Manser, Molli, Nika, Pierce, R. G. Huber, Sahai, Sch  fer, Scott, Smith, Stefan, Stork, T. Valovka, Taylor, Thaker, V. A. Bachmann, Wang, Wennerberg, Wong, Zenke, Zhang, Zhao   +47 more
core   +1 more source

Comprehensive Characterization of ^SGTP-Binding Proteins by Orthogonal Quantitative ^SGTP-Affinity Profiling and ^SGTP/GTP Competition Assays

Analytical Chemistry, 2014
Thiopurine drugs are widely used as antileukemic drugs and immunosuppressive agents, and 6-thioguanosine triphosphate ((S)GTP) is a major metabolite for these drugs. Recent studies have suggested that thiopurine drugs may exert their cytotoxic effects partly through binding of (S)GTP to a GTP-binding protein, Rac1.
Xiao, Yongsheng, Ji, Debin, Guo, Lei, Wang, Yinsheng   +3 more
openaire   +2 more sources