Results 11 to 20 of about 222,027 (284)

The speed of GTP hydrolysis determines GTP cap size and controls microtubule stability

open access: yeseLife, 2020
Microtubules are cytoskeletal polymers whose function depends on their property to switch between states of growth and shrinkage. Growing microtubules are thought to be stabilized by a GTP cap at their ends.
Johanna Roostalu   +5 more
doaj   +2 more sources

GTP-Dependent Formation of Multimeric G‑Quadruplexes

open access: yes, 2019
G-Quadruplexes are noncanonical nucleic acid structures made up of stacked guanosine tetrads connected by short loops. They are frequently used building blocks in synthetic biology and thought to play widespread biological roles.
Václav Veverka (1321008)   +5 more
core   +3 more sources

Adaptive smooth building method for 3D geological model based on geometric subdivision

open access: yesYantu gongcheng xuebao, 2023
The generalized triangular prism (GTP) voxel designed for the borehole data is the commonly method in the geological modelling, and it can be used to build the 3D solid geological model to express the stratigraphic space through the adjacent GTP voxel ...
SUN Liming 1, LIU Yushan 1, ZHANG Ruizhuo 2, YANG Yujian 3, YAN Jun 1
doaj   +1 more source

Efficacy and safety of Gutong Patch compared with NSAIDs for knee osteoarthritis: A real-world multicenter, prospective cohort study in China

open access: yesPharmacological Research, 2023
The Gutong Patch (GTP) is common in clinical practice for bone diseases. This study compared the efficacy and safety of GTP and nonsteroidal anti-inflammatory drugs (NSAIDs) for KOA patients from 35 medical centers assigned to GTP, selective COX-2 ...
Yingjie Wang   +5 more
doaj   +1 more source

GTP-Yeast Actin [PDF]

open access: yesJournal of Biological Chemistry, 2002
Because of the apparently greater conformational flexibility of yeast versus muscle actin and the ability of other members in the actin protein superfamily to efficiently use both ATP and GTP, we assessed the ability of yeast actin to function with GTP.
Kuo-Kuang, Wen   +2 more
openaire   +2 more sources

An integrated approach to infer cross-talks between intracellular protein transport and signaling pathways

open access: yesBMC Bioinformatics, 2018
Background The endomembrane system, known as secretory pathway, is responsible for the synthesis and transport of protein molecules in cells. Therefore, genes involved in the secretory pathway are essential for the cellular development and function ...
Kumar Parijat Tripathi   +2 more
doaj   +1 more source

A mant-GDP Dissociation Assay to Compare the Guanine Nucleotide Binding Preference of Small GTPases

open access: yesBio-Protocol, 2021
Small GTPases are cellular switches that are switched on when bound to GTP and switched off when bound to GDP. Different small GTPase proteins or those with mutations may bind to GTP or GDP with different relative affinities.
玉萍 tanyuping, Qingxiang Sun
doaj   +1 more source

Long-Term Cumulative Exposure to High γ-Glutamyl Transferase Levels and the Risk of Cardiovascular Disease: A Nationwide Population-Based Cohort Study [PDF]

open access: yesEndocrinology and Metabolism, 2023
Background Elevated γ-glutamyl transferase (γ-GTP) levels are associated with metabolic syndrome. We investigated the association of cumulative exposure to high γ-GTP with the risk of cardiovascular disease (CVD) in a large-scale population.
Han-Sang Baek   +7 more
doaj   +1 more source

Characterization of membrane-bound small GTP-binding proteins from Nicotiana tabacum [PDF]

open access: yes, 1995
Haizel T, Merkle T, Turck F, Nagy F. Characterization of membrane-bound small GTP-binding proteins from Nicotiana tabacum. Plant Physiology.
Haizel, T   +7 more
core   +1 more source

Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin

open access: yesBiomolecules, 2022
Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South ...
Kiran S. Toti   +4 more
doaj   +1 more source

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