Results 211 to 220 of about 386,929 (385)

Deciphering allosteric mechanisms in KRAS activation: insights from GTP-induced conformational dynamics and interaction network reorganization

Dongmei Zhao, Jingyu Yang, Meng-Ting Liu, Li-Quan Yang, Peng Sang   +4 more
openalex   +1 more source

Interleukin 1β and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells [PDF]

, 1996
Christoph Plüss, Ernst R. Werner, Nenad Blau, Helmut Wächter, Josef Pfeilschifter   +4 more
openalex   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

A special latch in yeast mitofusin guarantees mitochondrial fusion by stabilizing self-assembly. [PDF]

Nat Commun
Huang SJ, Ma DF, Yu C, Li J, Tu X, Huang Z, Qi Y, Ou JY, Feng JX, Yu B, Cao YL, Yue JX, Hu J, Li M, Lu Y, Yan L, Gao S.   +16 more
europepmc   +1 more source

Relative affinities of all Escherichia coli aminoacyl-tRNAs for elongation factor Tu-GTP.

, 1984
Alan Louie, N. Susan Ribeiro, Brian R. Reid, Frances Jurnak   +3 more
openalex   +1 more source

Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

Science, 2014
M. Boissan, Guillaume Montagnac, Q. Shen, L. Griparić, J. Guitton, M. Romao, N. Sauvonnet, T. Lagache, I. Lascu, G. Raposo, C. Desbourdes, U. Schlattner, M. Lacombe, Simona Polo, A. M. van der Bliek, Aurélien Roux, P. Chavrier   +16 more
semanticscholar   +1 more source

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

ARF: the most misunderstood GTPase I ever knew - why study ARF GAPs. [PDF]

Front Mol Biosci
Turn RE, Dacks JB, Rosenberg EM, Soubias O, Northup JK, Randazzo PA.   +5 more
europepmc   +1 more source

IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels. Indications of the regulation of GTP cyclohydrolase I activity by restriction of GTP availability in the cells.

, 1992
Kazuyuki Hatakeyama, T. Harada, Hiroyuki Kagamiyama   +2 more
openalex   +1 more source

Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium [PDF]

, 1998
Phil Oh, Deirdre P. McIntosh, Jan E. Schnitzer   +2 more
openalex   +1 more source