Results 81 to 90 of about 187,197 (244)
Effect of Adding Green Tea Polyphenols to Bali Bull Spermatozoa Diluent: Implications for Semen Quality, Hydrogen Peroxide Concentration, and Fertilization Rate [PDF]
Journal of Global Innovations in Agricultural SciencesGreen Tea Polyphenols (GTP) are bioactive compounds found in green tea and are known to have strong antioxidant properties. This study aims to determine the effectiveness of adding GTP in the extender in terms of quality, hydrogen peroxide (H2O2 ...
Yuni Sartika, Herry Sonjaya
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Advanced Science, EarlyView.Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng +17 more
wiley +1 more source
Going in GTP cycles in the nucleolus [PDF]
The Journal of Cell Biology, 2005 Proteins are directed to cellular compartments by specific localization signals. A GTP-driven cycle has now been identified as a mechanism for protein targeting to the nucleolus. The involvement of a GTP switch suggests that nucleolar localization can be regulated and may be responsive to extracellular stimuli via signaling pathways.
openaire +2 more sources
Advanced Science, EarlyView.Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu +9 more
wiley +1 more source
Advanced Science, EarlyView.Tpy–Zn complexes serve as versatile building blocks for the modular assembly of functional materials, including polymers, gels, MOFs, cages, and composites through programmed noncovalent interactions, empowering practical applications in visual molecular recognition, smart functional materials, and photocatalytic transformations. ABSTRACT As one of the
Lixin Duan +4 more
wiley +1 more source
eLife, 2017 Dynamin is a large GTPase that forms a helical collar at the neck of endocytic pits, and catalyzes membrane fission (Schmid and Frolov, 2011; Ferguson and De Camilli, 2012).
Valentina Galli +5 more
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Advanced Science, EarlyView.This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen +11 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2014 Background/Aims: Extracellular GTP is able to modulate some specific functions in neuron, glia and muscle cell models as it has been demonstrated over the last two decades.
Rosa Mancinelli +11 more
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From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics
Advanced Science, EarlyView.Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi +3 more
wiley +1 more source
Single‐Molecule Characterization of Bacterial Factor‐Dependent Transcription Activation by Rob
Advanced Science, EarlyView.Factor‐dependent transcription activation is crucial and involves complex interactions between transcription factors, RNA polymerase, and promoter DNA. Using single‐molecule assays, we show that Rob prebinds RNAP to facilitate promoter search and enhances DNA unwinding and promoter escape.
Yuqiong Zhang +7 more
wiley +1 more source