Regulation of phagocyte function by low molecular weight GTP‐binding proteins
European Journal of Haematology, 1993Abstract: The mechanisms used by phagocytic leukocytes in the process of bacterial killing are regulated by GTP‐binding proteins of the Ras superfamily. In particular, the formation of toxic oxygen metabolites via the NADPH oxidase requires the action of both Rac and Rap1A proteins.
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Tissue-specific variations in the expression and regulation of the small GTP-binding protein Rho
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1994Rho proteins are involved in the regulation of the assembly of the microfilamental cellular network and are known to be specific substrates for the ADP-ribosyltransferase C3 from Clostridium botulinum. Here, we studied the distribution of Rho and Rho-regulating proteins in extracts from various rabbit tissues.
G, Fritz, P, Lang, I, Just
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Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins
Biochemistry and Cell Biology, 2004The function of G protein-coupled receptors is regulated by a broad variety of membrane-bound and intracellular proteins. These act in concert to activate signaling pathways that will lead to the desensitization of activated receptors and, for most receptor types, their trafficking to intracellular compartments.
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Common Properties of Receptors Coupled to GTP Binding Regulator Proteins
1989A number of membrane receptors coupled to GTP binding regulatory proteins have recently been shown to share structural propertie at the level both of the genes and of the corresponding proteins (Fig. 1 and 2). By comparing results obtained for α2-, β1- and β2-adrenergic catecholamine receptors, M1 to M5 muscarinic acetylcholine receptors as well as ...
L. Emorine +6 more
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Rab3 Small GTP—Binding Proteins: Regulation by Calcium/Calmodulin
2003Rab proteins, forming a subfamily of 52 predominantly membrane-bound, low molecular weight GTP-binding proteins (G-proteins) of the Ras superfamily, are involved in vesicle traffic between intracellular organelles, endocytosis and exocytosis, and may be regulated by calcium (Ca2 +) and/or calmodulin (CaM).
Ranjinder S. Sidhu +2 more
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Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins
Current Opinion in Cell Biology, 1996Integrin signalling requires the activation of protein tyrosine kinases and members of the Rho family of small GTP-binding proteins. Recent evidence shows that coordinated regulation of these signalling molecules is central to the control of cell adhesion, formation of the actin cytoskeleton and activation of intracellular signalling cascades.
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Highlight: GTP Binding Proteins Central Regulators in Cell Biology
Biological Chemistry, 2000Wittinghofer, A., Gierschik, P.
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The GTP-binding protein, Go, regulates neuronal calcium channels.
Nature, 1987In neuronal cells, opioid peptides and opiates inhibit neurotransmitter release, which is a calcium-dependent process. They also inhibit adenylyl cyclase, presumably via the membrane signal-transducing component, Gi, a guanine nucleotide-binding protein (G-protein). No causal relationship between these two events has yet been demonstrated.
J, Hescheler +3 more
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Regulation of Rod GTP Binding Protein by Guanine Nucleotides1
The Journal of Biochemistry, 1984Hitoshi SHICHI, Robert L. SOMERS
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Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton
Annual Review of Cell Biology, 1994openaire +2 more sources