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Ras Superfamily Small G Proteins: Biology and Mechanisms 2, 2014
The Arf small GTP-binding (G) proteins regulate membrane traffic and organelle structure in eukaryotic cells through a regulated cycle of GTP binding and hydrolysis.
C. L. Jackson
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The Arf small GTP-binding (G) proteins regulate membrane traffic and organelle structure in eukaryotic cells through a regulated cycle of GTP binding and hydrolysis.
C. L. Jackson
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Rab3 Small GTP—Binding Proteins: Regulation by Calcium/Calmodulin
2003Rab proteins, forming a subfamily of 52 predominantly membrane-bound, low molecular weight GTP-binding proteins (G-proteins) of the Ras superfamily, are involved in vesicle traffic between intracellular organelles, endocytosis and exocytosis, and may be regulated by calcium (Ca2 +) and/or calmodulin (CaM).
Richard R. Clough+2 more
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Overexpression of developmentally regulated GTP-binding protein-2 increases bone loss
American Journal of Physiology-Endocrinology and Metabolism, 2013The developmentally regulated GTP-binding protein-2 (DRG2) is a novel subclass of GTP-binding proteins. Many functional characteristics of osteoclasts (OC) are associated with small GTPases. We hypothesized that DRG2 affects bone mass via modulating OC activity. Using DRG2 transgenic mice, we investigated the role of DRG2 in bone remodeling.
Hye-Seon Choi+9 more
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Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins
Biochemistry and Cell Biology, 2004The function of G protein-coupled receptors is regulated by a broad variety of membrane-bound and intracellular proteins. These act in concert to activate signaling pathways that will lead to the desensitization of activated receptors and, for most receptor types, their trafficking to intracellular compartments.
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A small GTP-binding protein dissociates from synaptic vesicles during exocytosis
Nature, 1991G. F. V. Mollard, T. Südhof, R. Jahn
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Study of Rab6, a Ras‐like GTP‐binding Protein Associated with the Golgi Complex
Annals of the New York Academy of Sciences, 1994B. Goud+4 more
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Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins
Current Opinion in Cell Biology, 1996Integrin signalling requires the activation of protein tyrosine kinases and members of the Rho family of small GTP-binding proteins. Recent evidence shows that coordinated regulation of these signalling molecules is central to the control of cell adhesion, formation of the actin cytoskeleton and activation of intracellular signalling cascades.
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Activation of a small GTP-binding protein by nucleoside diphosphate kinase.
Science, 1991P. Randazzo, J. Northup, R. A. Kahn
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The monomeric GTP binding protein, rab3a, is associated with the acrosome in mouse sperm
Molecular Reproduction and Development, 1999C. Ward, D. Faundes, J. Foster
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