Results 31 to 40 of about 328,040 (284)

Inhibitory Effects of Green Tea Polyphenols on Microbial Metabolism of Aromatic Amino Acids in Humans Revealed by Metabolomic Analysis

open access: yesMetabolites, 2019
The bioactivities and potential health benefits of green tea polyphenols (GTP) have been extensively investigated, but the metabolic impact of chronic GTP intake on humans is not well defined.
Yuyin Zhou   +3 more
doaj   +1 more source

Effect of Green Tea Powder on Physicochemical Properties and Glycemic Potential of Sponge Cake

open access: yesJournal of Food Quality, 2022
Green tea powder (GTP) is rich in polyphenolic compounds, most particularly catechins. The effects of partial replacement of flour with GTP (10, 20, and 30%) on physicochemical properties, glycemic potential, and sensory attributes were investigated ...
Mana Mashkour   +4 more
doaj   +1 more source

Citrate Regulates the Saccharomyces cerevisiae Mitochondrial GDP/GTP Carrier (Ggc1p) by Triggering Unidirectional Transport of GTP

open access: yesJournal of Fungi, 2022
The yeast mitochondrial transport of GTP and GDP is mediated by Ggc1p, a member of the mitochondrial carrier family. The physiological role of Ggc1p in S.
Roberta Seccia   +11 more
doaj   +1 more source

OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation [PDF]

open access: yes, 2010
The dynamin-related GTPase OPA1 is mutated in autosomal dominant optic atrophy (DOA) (Kjer type), an inherited neuropathy of the retinal ganglion cells.
Alexander   +28 more
core   +3 more sources

GTP cyclohydrolase I utilizes metal‐free GTP as its substrate [PDF]

open access: yesEuropean Journal of Biochemistry, 2003
GTP cyclohydrolase I (GCH) is the rate‐limiting enzyme for the synthesis of tetrahydrobiopterin and its activity is important in the regulation of monoamine neurotransmitters such as dopamine, norepinephrine and serotonin. We have studied the action of divalent cations on the enzyme activity of purified recombinant human GCH expressed in Escherichia ...
T. Suzuki, H. Kurita, H. Ichinose
openaire   +2 more sources

Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]

open access: yes, 1993
The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna   +5 more
core   +3 more sources

GTP-Dependent K-Ras Dimerization [PDF]

open access: yesStructure, 2015
Ras proteins recruit and activate effectors, including Raf, that transmit receptor-initiated signals. Monomeric Ras can bind Raf; however, activation of Raf requires its dimerization. It has been suspected that dimeric Ras may promote dimerization and activation of Raf.
Muratcioglu, Serena   +13 more
openaire   +2 more sources

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Regulation of local GTP availability controls RAC1 activity and cell invasion

open access: yesNature Communications, 2021
Changes in intracellular GTP levels are not considered as a regulatory event in RAC1 activation in live cells since total GTP levels are substantially higher than the RAC1 GTP dissociation constant determined in vitro.
Anna Bianchi-Smiraglia   +23 more
doaj   +1 more source

Game Transfer Phenomena and Problematic Interactive Media Use: Dispositional and Media Habit Factors

open access: yesFrontiers in Psychology, 2021
The study of the effects of interactive media has mainly focused on dysregulated behaviors, the conceptualization of which is supported by the paradigms of addiction.
Angelica B. Ortiz de Gortari   +1 more
doaj   +1 more source

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