Make and Break the Alarmone:regulation of (p)ppGpp Synthetase/Hydrolase Enzymes in Bacteria [PDF]
, 2019 Bacteria use dedicated mechanisms to respond adequately to fluctuating environments and to optimize their chances of survival in harsh conditions. One of the major stress responses used by virtually all bacteria relies on the sharp accumulation of an ...
Hallez, Régis, Ronneau, Séverin
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Les atrophies optiques héréditaires [PDF]
, 2010 IntroductionLes atrophies optiques héréditaires forment un groupe hétérogène de maladies responsables d’une dégénérescence des cellules ganglionnaires de la rétine avec une expression phénotypique variable, allant de formes asymptomatiques jusqu’à des ...
C. Scherer +8 more
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Standardized mitochondrial analysis gives new insights into mitochondrial dynamics and OPA1 function [PDF]
, 2012 Mitochondria form dynamic tubular networks through processes of fission and fusion. Defect in mitochondrial dynamics lead to various pathologies, including several common and some rare neurodegenerative disorders.
A. Chevrollier +9 more
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De la levure aux maladies neurodégénératives : Dix ans d’exploration des pathologies de la dynamique mitochondriale [PDF]
, 2010 Ten years ago, OPA1 was identified as the major gene responsible for hereditary optic nerve degeneration, evidencing the first defect in mitochondrial network dynamics as the princeps pathophysiological mechanism in a mitochondriopathy.
A. Chevrollier +9 more
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5'-nucleotidases, nucleosides and their distribution in the brain: pathological and therapeutic implications [PDF]
, 2013 Elements of the nucleoside system (nucleoside levels, 5'-nucleotidases (5'NTs) and other nucleoside metabolic enzymes, nucleoside transporters and nucleoside receptors) are unevenly distributed in the brain, suggesting that nucleosides have region ...
Dobolyi, Árpád +3 more
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The diguanylate cyclase AdrA regulates flagellar biosynthesis in Pseudomonas fluorescens F113 through SadB [PDF]
, 2019 Flagellum mediated motility is an essential trait for rhizosphere colonization by pseudomonads. Flagella synthesis is a complex and energetically expensive process that is tightly regulated.
Arrebola, Eva +8 more
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OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution [PDF]
, 2010 Eukaryotic cells harbor a small multiploid mitochondrial genome, organized in nucleoids spread within the mitochondrial network. Maintenance and distribution of mitochondrial DNA (mtDNA) are essential for energy metabolism, mitochondrial lineage in ...
A. Olichon +18 more
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Studies on OX1 Orexin Receptor Coupling to Arachidonic Acid and Endocannabinoid Signaling [PDF]
, 2012 Orexin A and orexin B are hypothalamic neuropeptides secreted by a relatively small group of neurons located within the hypothalamus. Orexins bind and activate two G-protein-coupled receptors termed OX1 orexin receptor and OX2 orexin receptor.
Turunen, Pauli
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Development of a Novel Lysophosphatidic Acid Activity Probe to Identify and Characterize New Protein Targets [PDF]
, 2009 Lipids are categorized according to their biological function. Phospholipids, glycolipids, and cholesterol are bulk membrane lipids that offer structure and support to the cells and organelle membranes.
Cuthriell, Leah M.
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Biochemical Markers of Lymphocyte Maturation [PDF]
, 2020 KováfiÛ H., F. KováfiÛ, A. Fi‰erová, P. Zelníãková, E. Matalová: Biochemical Markers of Lymphocyte Maturation. Acta Vet Brno 2002, 71: 503-508. We studied maturation-associated changes of cell membrane Na + , K + -and Mg 2+ -ATPase activities and gamma ...
A Fi·erová +4 more
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