Results 161 to 170 of about 258,313 (263)

Mebendazole Attenuates Cellular Invasion in a 3D Culture Model of Meningioma by Disrupting Rho-GTPase-Mediated Microtubule Function. [PDF]

Oncol Res
James MM, Clara Elena LV, Agadha W, Chuen CAH, Lee GC.   +4 more
europepmc   +1 more source

RHOV is a Detachment-Responsive Rho GTPase Necessary for Ovarian Cancer Peritoneal Metastasis. [PDF]

Cancer Res
Elhaw AT, Tang PW, Cheng YY, Kamlapurkar S, Javed Z, Al-Saad S, White SR, Abdelnaby AE, Khan H, Choi AS, Mattheyses AL, Cole AR, Kim YS, Atiya HI, Trebak M, Zervantonakis IK, Buckanovich RJ, Aird KM, Coffman LG, Mythreye K, Hempel N.   +20 more
europepmc   +1 more source

The small GTPase Rab5 inhibits actin polymerization mediated by the Legionella pneumophila effector VipA. [PDF]

Med Microbiol Immunol
Saraiva J, Bugalhão JN, Carvalho T, Hensel Z, Crevenna A, Mota LJ, Franco IS.   +6 more
europepmc   +1 more source

ARHGAP11A affects lung adenocarcinoma (LUAD) and pancreatic adenocarcinoma (PAAD) progression by regulating FAM83A. [PDF]

Transl Cancer Res
Sun K, Song LJ, Lu RQ, Liu QZ.
europepmc   +1 more source

Editorial: Reviews in ARF, the most misunderstood G protein I ever knew: a collection of papers exploring the multifaceted functions of an ancient protein family. [PDF]

Front Mol Biosci
Randazzo PA, Santy L, Chen PW.
europepmc   +1 more source

Rho GTPases signaling mediates aggressiveness and differentiation in neuroblastoma tumors. [PDF]

Cell Commun Signal
Gómez-Muñoz MA, Ojeda-Puertas M, Luna-Ramírez L, Amador-Álvarez A, Rodríguez-Prieto I, Cordero-Varela JA, Pardal R, Vega FM.   +7 more
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Profiling Ten RHO GTPases in Myeloid Malignancies Reveals Distinct Expression Patterns and Prognostic Associations. [PDF]

Cancer Med
de Almeida Rodrigues B, de Paiva LB, Ramalho MCC, Damasceno AF, Saad STO, Lazarini M.   +5 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Distinct steps of nuclear maturation of human pre-60S complexes require the activity of GTPases including GNL3L. [PDF]

Nucleic Acids Res
Thomé CC, Lemus-Diaz N, Bloch von Blottnitz KI, Tagnères S, Klein Helmkamp M, Honemann-Capito M, Hackert P, Moshkovskii S, Lenz C, Bohnsack MT, Urlaub H, Bohnsack KE.   +11 more
europepmc   +1 more source