Results 231 to 240 of about 322,041 (407)

Protein-Tyrosine Kinases Regulate the Phosphorylation, Protein Interactions, Subcellular Distribution, and Activity of p21^rasGTPase-Activating Protein [PDF]

, 1991
Michael F. Moran, Paul Polakis, Frank McCormick, Tony Pawson, Christine Ellis   +4 more
openalex   +1 more source

An Arabidopsis reticulon and the atlastin homologue RHD3-like2 act together in shaping the tubular endoplasmic reticulum [PDF]

, 2012
Avisar, Bian, Boevink, Brandizzi, Bubeck, Chen, Chen, Chris Hawes, Cola, DaSilva, Denecke, Hannah Lee, Hellens, Hu, Hu, Hu, Imogen Sparkes, Irons, Karimi, Knop, Kunkel, Lerich, Lilley, Lorenzo Frigerio, Lynne M. Roberts, Moss, Natasha Dzimitrowicz, Nziengui, Oda, Oertle, Orso, Pendin, Runions, Sparkes, Sparkes, Sparkes, Sparkes, Sparkes, Stefano, Stefano Gattolin, Tolley, Tolley, Voeltz, Wang, Zheng   +44 more
core   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, EarlyView.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Michaelis-Menten kinetics of RasGAP proteins by a rapid fluorescence-based assay. [PDF]

Methods
Paul ME, Vish KJ, Boggon TJ.
europepmc   +1 more source

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor.

Proceedings of the National Academy of Sciences of the United States of America, 2004
Yuan Gao, J. Dickerson, F. Guo, Jie Zheng, Yi Zheng   +4 more
semanticscholar   +1 more source

ACE‐mediated Glycosylation Stabilizes PSAP To Promote GPR37‐dependent Macrophage‐Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo, Feng Wang, Bijun Wang, Yu Zhou, Chao Wang, Tao Hu, Desheng Wu   +6 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

The role of small GTPases in Alzheimer's disease tau pathologies. [PDF]

Front Cell Neurosci
Hoegy P, Chen YH, Lu Q.
europepmc   +1 more source

Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain.

, 1993
Elisabeth T. Barfod, Yi Zheng, Wenhuan Kuang, Matthew J. Hart, Timothy A. Evans, Richard A. Cerione, Avi Ashkenazi   +6 more
openalex   +1 more source