Results 231 to 240 of about 278,687 (359)

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

In-silico, in-vitro, and proteomics analyses on repurposed drugs in targeting the small GTPase, Rho subfamily protein (Rho GTPase), and putative Rho GTPase-activating protein (RhoGAP) of Giardia lamblia. [PDF]

J Genet Eng Biotechnol
Jasni N, Abd Halim KB, Kin WW, Lau D, Young C, Hoffmann P, Othman N.   +6 more
europepmc   +1 more source

An Arabidopsis reticulon and the atlastin homologue RHD3-like2 act together in shaping the tubular endoplasmic reticulum [PDF]

, 2012
Avisar, Bian, Boevink, Brandizzi, Bubeck, Chen, Chen, Chris Hawes, Cola, DaSilva, Denecke, Hannah Lee, Hellens, Hu, Hu, Hu, Imogen Sparkes, Irons, Karimi, Knop, Kunkel, Lerich, Lilley, Lorenzo Frigerio, Lynne M. Roberts, Moss, Natasha Dzimitrowicz, Nziengui, Oda, Oertle, Orso, Pendin, Runions, Sparkes, Sparkes, Sparkes, Sparkes, Sparkes, Stefano, Stefano Gattolin, Tolley, Tolley, Voeltz, Wang, Zheng   +44 more
core   +1 more source

Overexpression of RhoA, Rac1, and Cdc42 GTPases Is Associated with Progression in Testicular Cancer [PDF]

, 2004
Takao Kamai, Tomonori Yamanishi, Hiromichi Shirataki, Kentaro Takagi, Hidekazu Asami, Yuji Ito, Ken‐Ichiro Yoshida   +6 more
openalex   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Rac1 selectively binds a specific lamellipodin isoform via a noncanonical helical interface. [PDF]

J Biol Chem
Gao T, Zhang P, Kurimchak AM, Duncan JS, Wu J.   +4 more
europepmc   +1 more source

GTPase-deficient G alpha i2 oncogene gip2 inhibits adenylylcyclase and attenuates receptor-stimulated phospholipase A2 activity

, 1991
Joseph M. Lowndes, Sunil Gupta, Shoji Osawa, Gary L. Johnson   +3 more
openalex   +1 more source

Rho Family Gtpase Cdc42 Is Essential for the Actin-Based Motility of Shigella in Mammalian Cells [PDF]

, 1999
Toshihiko Suzuki, Hitomi Mimuro, Hiroaki Miki, Tadaomi Takenawa, Takuya Sasaki, Hiroyuki Nakanishi, Yoshimi Takai, Chihiro Sasakawa   +7 more
openalex   +1 more source

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

Structural insights into GM4951 as a lipid droplet GTPase regulating hepatic lipid metabolism. [PDF]

Nat Commun
Raj R, Jiang Y, Jha RK, Moresco EMY, Joshi H, Zhang Z, Beutler B.   +6 more
europepmc   +1 more source