Results 231 to 240 of about 188,398 (263)

Macropinocytosis of Amyloid Precursor Protein Is Regulated by the Recruitment and Activity of Fe65, Arf6 and Rho GTPases. [PDF]

Cells
Krupa JM, Medapati MR, Naqvi AM, Hallam RD, Tsang AR, Seah C, Whitehead SN, Pasternak SH.   +7 more
europepmc   +1 more source

DNM2 lipid binding drives centronuclear myopathy and represents a potential therapeutic target. [PDF]

JCI Insight
Gómez-Oca R, Massana-Muñoz X, Reiss D, De Carvalho Neves J, Diedhiou N, Silva-Rojas R, Cowling BS, Goret M, Laporte J.   +8 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Editorial: Reviews in ARF, the most misunderstood G protein I ever knew: a collection of papers exploring the multifaceted functions of an ancient protein family

Frontiers in Molecular Biosciences
Paul A. Randazzo, Lorraine Santy, Pei-Wen Chen   +2 more
doaj   +1 more source

Machine Learning-Driven Drug Repurposing for KRAS G12C and KRAS G12D Inhibition. [PDF]

ACS Omega
Fuschi G, Germain JS, Bebensee D, Moawad C, Aladysheva A, Mohamed A, Brooks BR, Savai R, Elwakeel E, Amin M.   +9 more
europepmc   +1 more source

Mitochondrial resilience: a convergent framework for pathogenesis and neuroprotection in Parkinson's disease. [PDF]

Front Pharmacol
Arias-Carrión O, Guerra-Crespo M, Soto-Rojas LO, Valle Y, Ortega-Robles E, Ortuño-Sahagún D.   +5 more
europepmc   +1 more source

Mutational analysis of the mitotic exit GTPase MoTem1 reveals its role in development, stress adaptation, pathogenicity and global gene regulation in Magnaporthe oryzae. [PDF]

Stress Biol
Pei M, Xie X, Cao Y, Chen J, Yang F, Wang Z, Olsson S, Lu GD, Li Y.   +8 more
europepmc   +1 more source

Proteomic Dynamics Reveal Cell-Cycle and Rho GTPase Remodeling Associated with Transient Senescence Traits in Human Chondrocytes During Sustained IL-1β Signaling. [PDF]

Cells
Valerio HP, Corrêa de Melo T, Barbosa de Souza Rizzo M, Teixeira de Melo A, Alvarez-Flores MP, Chudzinski-Tavassi AM.   +5 more
europepmc   +1 more source

REAP1/AtSWAP70 integrates RAB5 and ROP signalling during sexual reproduction. [PDF]

Nat Plants
Ito E, Rzepecka NJ, Ito Y, Hirano T, Ebine K, Oda Y, Sato MH, Nakano A, Uemura T, Ueda T.   +9 more
europepmc   +1 more source

Enhancement of the leptomeninges in a young man

Brain Pathology, EarlyView.
Jayden Ray, Mohammad Alberawi, Andrew Bauer, Kar‐Ming Fung, Erika Santos Horta, Lorraina J. Robinson   +5 more
wiley   +1 more source