Results 261 to 270 of about 261,647 (345)

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Botulinum toxin-catalyzed ADP-ribosylation of Gb (rho gene product). 4. Partial purification and characterization of rho-specific GTPase Activating Protein (rho GAP)

, 1990
Akihiro Sekine, Shuh Narumiya, Motohatsu Fujiwara   +2 more
openalex   +1 more source

PKN2 Inhibits VEGFA and bFGF‐Mediated Angiogenesis by Targeting HIF‐1α in Colon Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Angiogenesis plays a vital role in colon cancer growth and metastasis. The role of protein kinase N2 (PKN2) in colon cancer is rarely studied. In this study, we investigated the effect of PKN2 on angiogenesis in colon cancer. We evaluated the correlation between PKN2 expression and microvessel density (MVD) in tumor tissue of patients with ...
Yun Zhu, Shi‐Yun Huang, Yi Lei, An‐Ni Luo, Xiang‐Zhao Li, Biao Wang, Peng‐Hui Sun, Si‐Tang Gong, Yang Cheng   +8 more
wiley   +1 more source

Sweet control: intracellular sorting of glycoproteins in plants. [PDF]

J Exp Bot
Qi W, Zhang B, Yue J, Zhang L.
europepmc   +1 more source

Mechanism of the microtubule GTPase reaction

, 1990
Michael Caplow, John Shanks
openalex   +2 more sources

Photoaffinity labeling coupled to MS to identify peptide biological partners: Secondary reactions, for better or for worse?

Mass Spectrometry Reviews, EarlyView.
Abstract Affinity photolabeling is a smart method to study noncovalent and transient interactions and provide a submolecular picture of the contacts between interacting partners. In this review, we will focus on the identification of peptide partners using photoaffinity labeling coupled to mass spectrometry in different contexts such as in vitro with a
Astrid Walrant, Emmanuelle Sachon
wiley   +1 more source

Understanding the Role of Rho GTPase Activating Protein and Bone Marrow Kinase X: A Novel Target in Gastric Cancer Treatment. [PDF]

Asian Pac J Cancer Prev
Shaibu Z, Chen Z, Yang F, Xu X, Ji Y, Zhu W.   +5 more
europepmc   +1 more source

Proliferation and differentiation of rat pheochromocytoma PC12 cells were affected by the overexpression of p21ras GTPase activating proteins or expression of its deletion mutant proteins.

, 1994
Hiroko Nakata, Hidenori Sasa, Koji Tomiyama, Yasuhiro Watanabe   +3 more
openalex   +1 more source

Restoration of Miro1's N-terminal GTPase function alleviates prenatal stress-induced mitochondrial fission via Drp1 modulation. [PDF]

Cell Commun Signal
Choi GE, Park JY, Park MR, Chae CW, Jung YH, Lim JR, Yoon JH, Cho JH, Han HJ.   +8 more
europepmc   +1 more source