Results 271 to 280 of about 261,647 (345)

Distribution of p21ras GTPase-activating protein-like immunoreactivities in mouse brain in the reverse tolerance induced by methamphetamine.

, 1994
Misako Namima, Hidenori Sasa, Hiroko Nakata, Mariko Yamano, Yasuhiro Watanabe   +4 more
openalex   +1 more source

Coexistence of APC and KRAS Mutations in Familial Adenomatous Polyposis and Endometrial Cancer: A Mini‐Review With Case‐Based Perspective

Med Research, EarlyView.
ABSTRACT Familial adenomatous polyposis (FAP) is a well‐characterized hereditary colorectal cancer syndrome driven by germline mutations in the APC gene. KRAS mutations, although more common in sporadic colorectal and endometrial cancers, are rarely seen concurrently in patients with FAP.
Tongchuan Yin, Zhenhua Tan, Lanjin Bai, Haibo Lan, Tianliang Liu   +4 more
wiley   +1 more source

OPA1 mutations in dominant optic atrophy: domain-specific defects in mitochondrial fusion and apoptotic regulation. [PDF]

J Transl Med
Zhang K, Zhang W, Zhang L, Hou X, Tian R, Hu Z, Yin L, Hu Z.   +7 more
europepmc   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

Medicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi, Yangzhi Cao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs   +4 more
wiley   +1 more source

Dynamin2 mutations in newly diagnosed acute myeloid leukemia: clinical characteristics, and prognostic significance. [PDF]

Exp Hematol Oncol
Luo K, Chen J, Wang W, Hui Y, Qiu S, Liu B, Mi Y, Wang J, Wei H.   +8 more
europepmc   +1 more source

Suppression of yeast geranylgeranyl transferase I defect by alternative prenylation of two target GTPases, Rho1p and Cdc42p.

, 1993
Yoshikazu Ohya, Hiroshi Qadota, Yasuhiro Anraku, John R. Pringle, David Botstein   +4 more
openalex   +2 more sources

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

, 1995
Caroline S. Hill, Judy Wynne, Richard Treisman   +2 more
openalex   +1 more source

Defining the Molecular Impacts of Humalite Application on Field‐Grown Wheat (Triticum aestivum L.) Using Quantitative Proteomics

PROTEOMICS, EarlyView.
ABSTRACT Increasing global food production demands have resulted in increased fertilizer usage, causing detrimental environmental impacts. Biostimulants, such as humic substances, are currently being applied as a strategy to increase plant nutrient‐use efficiency and minimize environmental impacts within cropping systems.
Lauren E. Grubb, Mohana Talasila, Linda Y. Gorim, Richard Glen Uhrig   +3 more
wiley   +1 more source

First molecules to reactivate RAS^G12V GTPase activity. [PDF]

BMC Cancer
Wlodarczyk A, Treda C, Pacholczyk M, Rutkowska A, Wegierska M, Kierasinska-Kalka A, Wasiak K, Ciunowicz D, Grot D, Glowacki P, Stoczynska-Fidelus E, Rieske P.   +11 more
europepmc   +1 more source