Results 291 to 300 of about 261,647 (345)
Plasma Proteomic Profiling of a Group of Anxious Dogs by LC‐MS/MS: A Case–Control Study
ABSTRACT Purpose Anxiety is the most common underlying cause of behavioral problems in dogs, which remain a top reason for relinquishment and euthanasia. Despite its high prevalence, anxiety is often underdiagnosed, partly due to a limited understanding of biological processes and absence of diagnostic biomarkers.
Claudia Gaither+4 more
wiley +1 more source
Evolutionary insights into elongation factor G using AlphaFold and ancestral analysis. [PDF]
Rahaman S+4 more
europepmc +1 more source
Mitochondrial dynamics in autoimmune diseases
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma+5 more
wiley +1 more source
AptERA 2 targets ERA from Staphylococcus aureus and limits GTP hydrolysis
Peñaranda K+6 more
europepmc +1 more source
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong+4 more
wiley +1 more source
Targeting Gene <i>C9orf72</i> Pathogenesis for Amyotrophic Lateral Sclerosis. [PDF]
Chong ZZ, Souayah N.
europepmc +1 more source
Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle
Current model on the effects of acute endurance exercise on the AS regulatory mechanism with key trans‐factors/RBPs (e.g., hnRNP‐A1, ‐A3, and TIA1). ABSTRACT Alternative splicing (AS) is a highly conserved posttranscriptional mechanism, generating mRNA variants to diversify the proteome.
Alexander Ahn+5 more
wiley +1 more source
RAC2 inhibition enhances tumor sensitivity to NK cell-mediated cytotoxicity. [PDF]
Guo H+16 more
europepmc +1 more source
This study reveals that in vitro senescence induction methods significantly influence intracellular biomolecular profiles, showing both shared and unique metabolic responses. A novel bioanalytical pipeline was developed to explore these subphenotypes, highlighting the importance of targeting metabolic redox circuits and serine/taurine pathways for ...
Domenica Berardi+11 more
wiley +1 more source