Results 301 to 310 of about 274,715 (359)
An apicoplast-localized GTPase is essential for Toxoplasma gondii survival. [PDF]
mSphereGriffith MB +3 more
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Distinct Cdc42 protein levels differentially regulate polarized growth and cell fusion in Schizosaccharomyces pombe. [PDF]
PLoS BiolSaha S +4 more
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Current Opinion in Structural Biology, 1995
The past year has witnessed a tremendous increase in our understanding of the structures and interactions of the GTPases. The highlights include crystal structures of G alpha subunits, as well as the first complex between a GTPase (Rap1A) and an effector molecule (c-Raf1 Ras-binding domain).
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The past year has witnessed a tremendous increase in our understanding of the structures and interactions of the GTPases. The highlights include crystal structures of G alpha subunits, as well as the first complex between a GTPase (Rap1A) and an effector molecule (c-Raf1 Ras-binding domain).
openaire +2 more sources
2017
GTPases (GTP hydrolases, GTP binding proteins) are a large family of enzymes that direct various cellular functions, including signal transduction, protein biosynthesis, cell division and transport of vesicles. They are molecular switches that cycle between two conformational states (Figure 1): the inactive guanosine-5'-diphosphate (GDP)-bound state ...
Stefanini, Lucia +2 more
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GTPases (GTP hydrolases, GTP binding proteins) are a large family of enzymes that direct various cellular functions, including signal transduction, protein biosynthesis, cell division and transport of vesicles. They are molecular switches that cycle between two conformational states (Figure 1): the inactive guanosine-5'-diphosphate (GDP)-bound state ...
Stefanini, Lucia +2 more
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The Interferon-Inducible GTPases
Annual Review of Cell and Developmental Biology, 2006Mammalian cells respond to interferons (IFNs) secreted during infection by the transcriptional upregulation of as many as a thousand genes. This remarkable transition prepares cells and organisms for resistance to infection, and many IFN-regulated gene products are players in well-understood resistance programs.
Martens, Sascha, Howard, Jonathan
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Biochemical Society Transactions, 2012
Rho GTPases comprise a family of molecular switches that control signal transduction pathways in eukaryotic cells. A conformational change induced upon binding GTP promotes an interaction with target (effector) proteins to generate a cellular response. A highly conserved function of Rho GTPases from yeast to humans is to control the actin cytoskeleton,
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Rho GTPases comprise a family of molecular switches that control signal transduction pathways in eukaryotic cells. A conformational change induced upon binding GTP promotes an interaction with target (effector) proteins to generate a cellular response. A highly conserved function of Rho GTPases from yeast to humans is to control the actin cytoskeleton,
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The Journal of the Florida Medical Association, 1993
GTPases represent a large family of proteins involved in a wide variety of cellular processes. They function as switches in which they are "on" in the GTP bound state and "off" in the GDP bound state. The "on" and "off" states are regulated by proteins which interact with the GTPases and enhance their rate of either GTP hydrolysis or GDP-GTP exchange ...
R K, Keller, M, Standert
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GTPases represent a large family of proteins involved in a wide variety of cellular processes. They function as switches in which they are "on" in the GTP bound state and "off" in the GDP bound state. The "on" and "off" states are regulated by proteins which interact with the GTPases and enhance their rate of either GTP hydrolysis or GDP-GTP exchange ...
R K, Keller, M, Standert
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2000
Abstract GTPases are molecular switches that are used to control biochemical pathways. This book describes the properties and cellular roles of all the major families of GTPases: the G proteins, Ras, Rho, Rab, Arf, and Ran. All cells use GTPases to regulate the delivery of amino acids to the ribosome during protein synthesis, but ...
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Abstract GTPases are molecular switches that are used to control biochemical pathways. This book describes the properties and cellular roles of all the major families of GTPases: the G proteins, Ras, Rho, Rab, Arf, and Ran. All cells use GTPases to regulate the delivery of amino acids to the ribosome during protein synthesis, but ...
openaire +1 more source