Results 301 to 310 of about 322,041 (407)

Botulinum toxin-catalyzed ADP-ribosylation of Gb (rho gene product). 4. Partial purification and characterization of rho-specific GTPase Activating Protein (rho GAP)

, 1990
Akihiro Sekine, Shuh Narumiya, Motohatsu Fujiwara   +2 more
openalex   +1 more source

Rab GTPase regulation of membrane identity.

Current Opinion in Cell Biology, 2013
S. Pfeffer
semanticscholar   +1 more source

Breaking barriers: the cGAS‐STING pathway as a novel frontier in cancer immunotherapy

Cancer Communications, EarlyView.
Abstract Since its discovery, the cyclic GMP‐AMP synthase (cGAS)‐stimulator of the interferon gene (STING) signaling pathway has been considered a pivotal component of innate immunity and a promising target for cancer immunotherapy. Beyond its canonical role in pathogen defense, accumulating evidence has demonstrated that the cGAS‐STING pathway ...
Yuheng Yan, Ximin Tan, Bin Song, Ming Yi, Qian Chu, Kongming Wu   +5 more
wiley   +1 more source

ADP ribosylation factor-like GTPase 6-interacting protein 5 (ARL6IP5): a prenylated Rab acceptor protein 1 (PRA1) family protein that shapes the ER membrane and regulates ER-phagy. [PDF]

Autophagy Rep
Yamamoto Y, Sakisaka T.
europepmc   +1 more source

Mechanism of the microtubule GTPase reaction

, 1990
Michael Caplow, John Shanks
openalex   +2 more sources

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

EMBO Journal, 1994
H. Stenmark, R. Parton, O. Steele‐Mortimer, A. Lütcke, J. Gruenberg, M. Zerial   +5 more
semanticscholar   +1 more source

Development and Validation of a High‐Throughput Screening Assay for the Legionella ADP‐Ribosyl Transferase SdeA

ChemBioChem, EarlyView.
We show the optimization and application of a fluorogenic assay to monitor Legionella SdeA activity in a High‐Throughput‐Screening campaign. Ubiquitination of proteins is one of the most crucial post‐translational modifications in eukaryotic cells, typically involving conjugation of ubiquitin to a lysine residue in a substrate using a three‐enzyme ...
Halana C. Vlaming, Vito Pol, Bjorn R. van Doodewaerd, Angeliki Moutsiopoulou, Paul P. Geurink, Robbert Q. Kim, Gerbrand J. van der Heden van Noort   +6 more
wiley   +1 more source

Loss-of-function coding variants in the Ras of complex proteins/GTPase domain of leucine rich repeat kinase 2. [PDF]

Protein Sci
Butterfield S, Herbst S, Lewis PA.
europepmc   +1 more source

Proliferation and differentiation of rat pheochromocytoma PC12 cells were affected by the overexpression of p21ras GTPase activating proteins or expression of its deletion mutant proteins.

, 1994
Hiroko Nakata, Hidenori Sasa, Koji Tomiyama, Yasuhiro Watanabe   +3 more
openalex   +1 more source

Phosphorylation at the Helm: Kinase‐Mediated Regulation of Primary Cilia Assembly and Disassembly

Cytoskeleton, EarlyView.
ABSTRACT The primary cilium serves as an antenna of most vertebrate cells and is important for conveying cues from several signaling pathways into appropriate cellular responses during development and homeostasis. Cilia assembly and disassembly processes are thought to be strictly controlled; however, the precise nature of molecular events underlying ...
Andrea Lacigová, Lukáš Čajánek
wiley   +1 more source