Guanidine-Based Ligands in Bioinorganic Chemistry: Coordination Modes and Applications in Anticancer Metallodrugs [PDF]
Bioinorganic Chemistry and ApplicationsGuanidine-containing molecules represent a versatile class of nitrogen-rich compounds whose unique structural and physicochemical features underpin a rich and tunable coordination chemistry.
Almudena del Campo-Balguerías +3 more
doaj +2 more sources
Evaluation of Antileishmanial and Antibacterial Activity of Bioconjugate Guanidine–Temporin [PDF]
PharmaceuticalsBackground: Peptides are promising tools in medicine for viral, bacterial, and parasitic infections. MAP1 and MAP2 are peptides with antimicrobial activity.
Gabriel Antunes Santoro +12 more
doaj +2 more sources
Improvement in heavy metal removal from aqueous solution using polyetherimide nanofiltration membrane modified by coating approach [PDF]
Journal of Applied Research in Water and Wastewater, 2022 This research focused on improving the antifouling properties and rejection performance of polyetherimide (PEI) nanofiltration membrane by chemical surface modification (surface coating).
Madineh Sadeghipour +2 more
doaj +1 more source
A variant of guanidine-IV riboswitches exhibits evidence of a distinct ligand specificity
RNA Biology, 2023 Riboswitches are regulatory RNAs that specifically bind a small molecule or ion. Like metabolite-binding proteins, riboswitches can evolve new ligand specificities, and some examples of this phenomenon have been validated.
Felina Lenkeit +5 more
doaj +1 more source
Guanidine-Containing Antifungal Agents against Human-Relevant Fungal Pathogens (2004–2022)—A Review
Journal of Fungi, 2022 The guanidine moiety is typically a highly basic group, and can be found in a wide variety of drugs, such as zanamivir (Relenza) and metformin (Fortamet), as well as in biologically active compounds for numerous disease areas, including central nervous ...
Simon D. P. Baugh
doaj +1 more source
Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses
Molecules, 2021 Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir. However, the current drugs are ineffective against latent and drug-resistant HSV infections.
Anita Toscani +6 more
doaj +1 more source
Evaluation of guanidine antifungal solutions for denture base resin: an in vitro study
Revista da Faculdade de Odontologia de Porto Alegre, 2020 Background: The purposes of this study were: (1) to formulate polyhexamethylene guanidine hydrochloride (PHMGH) solutions at different concentrations; (2) to evaluate their antifungal activity against a mature biofilm of Candida albicans on acrylic ...
Maria Eduarda Rodrigues Gama +4 more
doaj +1 more source
Isopropoxy Benzene Guanidine Kills Staphylococcus aureus Without Detectable Resistance
Frontiers in Microbiology, 2021 Serious infections caused by multidrug-resistant Staphylococcus aureus clearly urge the development of new antimicrobial agents. Drug repositioning has emerged as an alternative approach that enables us to rapidly identify effective drugs.
Xiufeng Zhang +11 more
doaj +1 more source
Molecules, 2016 Cyanation reactions of carbonyl compounds with methyl cyanoformate or acetyl cyanide catalyzed by 5 mol % of 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) were examined.
Satoru Matsukawa +2 more
doaj +1 more source
Antitumor, Antioxidant and Antimicrobial Studies of Substituted Pyridylguanidines
Molecules, 2013 A series of N-pivaloyl-N′-(alkyl/aryl)-N′′-pyridylguanidine of general formula C4H9CONHC(NR1R2)NPy have been synthesized and characterized using elemental analysis, FT-IR, multinuclear NMR spectroscopy, and in the case of compounds 7 and 11, by single ...
Boris Vabre +7 more
doaj +1 more source