Results 111 to 120 of about 68,963 (231)

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil   +7 more
wiley   +1 more source

Guanidine and guanidinium cation in the excited state—theoretical investigation

open access: yes, 2014
Diverse ab initio and density-functional-theory methods were used to investigate geometries, energies, and electronic absorption spectra of guanidine and its protonated form, as well as their photo-deactivation processes.
Crespo-Otero, R.   +7 more
core   +1 more source

A Morphological Study of Restoration of Damaged Hair Fiber With Chemical Treatments Using Microscopy Techniques

open access: yesMicroscopy Research and Technique, EarlyView.
Assessment of Restoring Chemically Damaged Hair Fibers Using Microscopy and Spectroscopy. ABSTRACT This paper analyses hair restoration products currently on the market that treat chemically processed hair. This study measured the restoration of structural integrity in hair samples from both chemically damaged hair (chemically relaxed, bleached, and ...
L. P. A. Mauricio   +2 more
wiley   +1 more source

Polycyclic Guanidine Alkaloids from Poecilosclerida Marine Sponges

open access: yes, 2016
Sessile marine sponges provide an abundance of unique and diversified scaffolds. In particular, marine guanidine alkaloids display a very wide range of biological applications.
Mohamed Mehiri   +3 more
core   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli   +7 more
wiley   +1 more source

Thiolate Salt Mediated Dynamic Silyl Ether Exchanges for Polymer Network Design and Deconstruction

open access: yesMacromolecular Rapid Communications, EarlyView.
This work introduces thiolate salts as mediators for dynamic silyl ether exchange. This platform enables the synthesis of reprocessable covalent adaptable polymer networks (CANs) and allows for sterically controlled, and tunable deconstruction of silyl ether‐containing thermosets.
Pierce T. Bombard   +9 more
wiley   +1 more source

Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery

open access: yesInternational Journal of Nanomedicine, 2016
Jiankun Yu,1 Jinmin Zhang,1 Haonan Xing,1 Zhen Yang,1 Cuifang Cai,1 Conglu Zhang,1 Xiaoyun Zhao,1 Minjie Wei,2 Li Yang,1 Pingtian Ding1 1School of Pharmacy, Shenyang Pharmaceutical University, 2School of Pharmacy, China Medical University, Shenyang ...
Yu J   +9 more
doaj  

A Chemically Recyclable 1,3,5‐Triazine‐Based Epoxy Thermoset Enabled by Nucleophilic Aromatic Substitution Reaction

open access: yesMacromolecular Rapid Communications, EarlyView.
High‐performance 1,3,5‐triazine epoxy networks are prepared via solvent‐free curing and recycled using nucleophilic aromatic substitution (SNAr) chemistry. This robust thermoset undergoes clean depolymerization into well‐defined building blocks for seamless repolymerization, achieving chemical recycling while preserving thermomechanical performance ...
Yi‐Ru Chen   +3 more
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

Structural basis for ligand binding to the guanidine-II riboswitch

open access: yes, 2017
The guanidine-II riboswitch, also known as mini-ykkC, is a conserved mRNA element with more than 800 examples in bacteria. It consists of two stem–loops capped by identical, conserved tetraloops that are separated by a linker region of variable length ...
Caroline W. Reiss, Scott A. Strobel
core   +1 more source

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