Results 91 to 100 of about 68,963 (231)

Guanidine-Containing Polyhydroxyl Macrolides: Chemistry, Biology, and Structure-Activity Relationship

open access: yesMolecules, 2019
Antimicrobial resistance has been seriously threatening human health, and discovering new antimicrobial agents from the natural resource is still an important pathway among various strategies to prevent resistance.
Xiaoyuan Song   +3 more
doaj   +1 more source

Guanidine-mediated unfolding of PriA.

open access: yes, 2015
D. radiodurans PriA was incubated with indicated concentrations of guanidine-HCl and PriA’s intrinsic fluorescence was measured as described in Materials and Methods. The inset shows the fluorescence emission spectrum for D.
Jacob Boone (771463)   +2 more
core   +1 more source

Chemical and Physical Tailoring of Guanidine-based Covalent Adaptable Networks [PDF]

open access: yes, 2022
We present the synthesis of two different guanidine-based CAN materials which, unlike traditional thermoset polymer networks, can undergo an exchange reaction called thermal guanidine metathesis (TGM) and be reprocessed.
Larsen, Michael B., McConnell, Kate A.
core  

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

open access: yesBMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang   +11 more
wiley   +1 more source

Cross‐Dehydrogenative Coupling Reactions With Redox‐Active Guanidine Reagents

open access: yesChemistry – A European Journal, EarlyView.
ABSTRACT Cross‐dehydrogenative coupling (CDC) reactions are attractive and environmentally friendly ways to form new C‐C and other element‐element bonds. Here, we report the first CDC reactions triggered by a redox‐active guanidine reagent. N‐phenyltetrahydroisoquinoline and derivatives with electron‐donating and withdrawing substituents at the N ...
Petra Walter   +2 more
wiley   +1 more source

Desenvolvimento de abordagem objetivando a síntese da 3-desidroxi-4-metoxi-tubastrina Development of an approach for the synthesis of 3-dehydroxy-4methoxy tubastrine

open access: yesQuímica Nova, 2007
We report the synthesis of amino(2-hydroxy-2-(4-methoxyphenyl)ethylamino)methaniminium (14) as a direct precursor of a tubastrine derivative (3-dehydroxy-4-methoxytubastrine). The synthetic steps involved functional group interconversions starting from 1-
Kelly de Oliveira Santos   +2 more
doaj   +1 more source

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

open access: yesChemistry – A European Journal, EarlyView.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

X-ray Structure of Eleven New N,N′-Substituted Guanidines: Effect of Substituents on Tautomer Structure in the Solid State

open access: yesCrystals
Guanidine-containing molecules are an interesting class of compounds within both medicinal and material sciences. Having knowledge of their tautomerism is key in designing guanidines that interact with biological and chemical receptors.
Vijayaragavan Elumalai   +6 more
doaj   +1 more source

Novel Effects Of Guanidine On The Neuromuscular Junction.

open access: yes, 2015
1. The effects of guanidine on the isolated mouse phrenic nerve diaphragm (MPND) and chick biventer cervicis (CBC) neuromuscular preparations were determined by myographic and electrophysiological methods. 2.
Prado-Franceschi, J   +7 more
core   +2 more sources

The Radical Chemistry of 2,3‐Diguanidinopyridines: Coordination and Visible‐Light Photochemistry

open access: yesChemistry – A European Journal, EarlyView.
Substitution at the pyridine core of 2,3‐diguanidinopyridines was used to develop novel redox‐active molecules with three interconvertible redox states. They are applied as redox‐active ligands in coordination chemistry. Visible‐light irradiation of the pyridine N‐benzylated molecules leads to photoconversion to a higher‐energetic isomer.
Hanna Koepcke   +3 more
wiley   +1 more source

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