Results 71 to 80 of about 68,963 (231)

Synthesis, Characterization and Docking Study of Novel Pyrimidine Derivatives as Anticancer Agents

Indonesian Journal of Chemistry, 2020
New compounds 5 and 9 using DNA bases e.g. Adenine 1 and Guanine 6 derivatives have been synthesized. The use of simple methods to synthesize compounds 5 and 9 were done using pyrimidine as an alternative DNA base ring.
Manal Mohamed Talaat El-Saidi, Ahmed Ali El-Sayed, Erik Bjerregaard Pedersen, Mohamed Abdelhamid Tantawy, Nadia Ragab Mohamed, Wafaa Ahmed Gad   +5 more
doaj   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Guanidinium phenylarsonate–guanidine–water (1/1/2) [PDF]

, 2010
In the structure of the title compound, CH6N3+·C6H6AsO3−·CH5N3·2H2O, the phenylarsonate anion participates in two R22(8) cyclic hydrogen-bonding interactions, one with a guanidinium cation, the other with a guanidine ...
Urs D. Wermuth, Smith, Graham, Wermuth, Urs D., Graham Smith   +3 more
core   +1 more source

Dry‑Contact Trimming for All‑Perovskite Tandem Solar Cells via Solid‑Solution Homogenization

Advanced Energy Materials, EarlyView.
Narrow‐bandgap Sn–Pb perovskites are promising bottom absorbers for all‐perovskite tandems but suffer from Sn‐rich surfaces and depth‐dependent lattice/compositional inhomogeneity. Layered‐perovskite‐assisted dry‐contact trimming removes Sn‐rich surface species and reconfigures the Sn–Pb absorber, enabling efficient charge collection, reduced voltage ...
Woocheol Han, Hyojin Hong, Chan Young Kim, Chan Ho Shin, Sung Yong Kim, So Eun Shin, Minhyeok Park, Giseon Yu, Sohyun Kang, Seungmin Lee, Jun Hong Noh   +10 more
wiley   +1 more source

Quantification of guanidine in environmental samples using benzoin derivatization and LC-MS analysis

MethodsX
The recent discovery of guanidine-dependent riboswitches in many microbes raised interest in the biological function and metabolism of this nitrogen-rich compound.
Richard Gruseck, Marton Palatinszky, Michael Wagner, Thilo Hofmann, Michael Zumstein   +4 more
doaj   +1 more source

Exploring 3D-QSAR to identify potential small molecule for treating Alzheimer disease: A case study with b-secretase inhibitors [PDF]

Scripta Medica
Background/Aim: One of the most common neurological conditions that results in dementia is Alzheimer disease. The current treatment options for Alzheimer disease include acetylcholinesterase (AChE) and -methyl-D-aspartate (NMDA) inhibitors, but there is ...
More Uttam A., Patel Maitri, Patel Krishna, Patel Harsiddhi, Patel Kruti Y., Jain Neha, Khan Shabeena, Vasandiya Kinjal, Noolvi Malleshappa N., Palkar Mahesh B.   +9 more
doaj   +1 more source

Modification of the existing maximum residue level for dodine in honey

EFSA Journal
In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Arysta Lifescience Benelux Srl submitted a request to the competent national authority in Spain to modify the existing maximum residue level (MRL) for the active substance dodine ...
European Food Safety Authority (EFSA), Giulia Bellisai, Giovanni Bernasconi, Irene Castellan, Monica delAguila, Lucien Ferreira, Renata Leuschner, Andrea Mioč, Marta Szot, Manuela Tiramani, Alessia Verani   +10 more
doaj   +1 more source

Synthesis of rigidified flavin–guanidinium ion conjugates and investigation of their photocatalytic properties

Beilstein Journal of Organic Chemistry, 2009
Flavin chromophores can mediate redox reactions upon irradiation by blue light. In an attempt to increase their catalytic efficacy, flavin derivatives bearing a guanidinium ion as oxoanion binding site were prepared.
Harald Schmaderer, Mouchumi Bhuyan, Burkhard König   +2 more
doaj   +1 more source

A Mild and Regioselective Ring-Opening of Aziridines with Acid Anhydride Using TBD or PS-TBD as a Catalyst

Molecules, 2015
The ring-opening of N-tosylaziridines with various acid anhydrides catalyzed by 5 mol % of 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding β-amino esters in excellent yields under mild reaction conditions. Polymer-supported catalyst,
Satoru Matsukawa, Yasutaka Mouri
doaj   +1 more source

Breaking the Ceiling of Boron-Boron Bonds: Understanding and Fine-Tuning Basicity in Diborane(4) Complexes. [PDF]

J Comput Chem
Diborane(4) can form strong complexes with one or two nitrogen bases, and still behave as a boron base. Complexed with two nitrogen bases, diborane(4) may reach very high proton affinities, overcoming that of the typical 1,8‐bis(dimethylamino)naphthalene super sponge. However, understanding basicity trends is not straightforward, due to the loss of the
Yáñez M, Mó O, Montero-Campillo MM, Alkorta I.   +3 more
europepmc   +2 more sources