Results 121 to 130 of about 68,963 (231)
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Artificial protein design enables the creation of stable scaffolds beyond those evolved in nature. Incorporation of native functional motifs into de novo scaffolds provides a promising strategy to mimic natural interactions while altering structural frameworks.
Hakuto Miyoshi +7 more
wiley +1 more source
Pest Management Science, EarlyView.Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus +13 more
wiley +1 more source
Pest Management Science, EarlyView.UV mutagenesis of Streptomyces sp. KRA0514‐6 yielded HL‐3, a novel streptothricin‐like compound (C17H29N7O8) with N‐methylglycine replacing β‐lysine, achieving 100% cabbage soft rot control at >1 ppm concentration. Abstract BACKGROUND A total of 1000 soil‐derived actinomycetes were isolated and screened for antibacterial activity against Pectobacterium
Young Sook Kim +5 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, EarlyView.ABSTRACT Rationale Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry‐based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition.
Annelaure Damont +9 more
wiley +1 more source
Responsive Materials, EarlyView.Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
Small, EarlyView.A photoreversible 1D protein assembly has been developed by utilizing symmetry matching between StrepTactin and photoswitchable Dronpa145N. The light‐induced modulation of oligomerization allows for precise control over protein connectivity and valency.
Jangwon Bae, Yongwon Jung
wiley +1 more source
Oppositely Charged Homopolypeptides Form Ordered Helix Assemblies With Hierarchical Structure
Small, EarlyView.Hexagaonal and square assembly of polyarginine alfa‐helices formed in highly ordered polyarginine/polyaspartic acid complexes. The helices exhibit additional periodic staggering along their helical axis. ABSTRACT Oppositely charged polyelectrolytes are known to form polyelectrolyte complexes.
Ekaterina Buvalaia +10 more
wiley +1 more source
Small Methods, EarlyView.Nature‐inspired bi‐functionalized magnetic nanoparticles are engineered for the rapid, non‐invasive extraction of cell‐free DNA from unprocessed urine for liquid biopsy. These cationic particles leverage electrostatic interactions to outperform conventional kits, enhancing the recovery of short DNA fragments while maintaining DNA integrity.
Dina Haddad +4 more
wiley +1 more source
Design and biological evaluation of novel guanidine-decorated bispidinic structures
LAUREA MAGISTRALELe bispidine sono una classe di molecole organiche caratterizzate da una struttura tridentata basata sul 3,7-diazabiciclo[3.3.1]nonano.
Colombo, Andrea
core
Transformative Chemistry, EarlyView.Direct asymmetric α‐C conjugate addition of aminoacetonitrile enabled by carbonyl/iminium double activation, together with subsequent electrophilic functionalization, offers a one‐pot, two‐step modular strategy for synthesizing chiral α‐quaternary pyrrolines with precise chirality relay and high structural diversity.
Xingdie Yang +6 more
wiley +1 more source