Results 141 to 150 of about 57,067 (241)

The Role of Meprins on the Brain Extracellular Matrix and Perineuronal Nets

open access: yesThe FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Meprin β overexpression is implicated in Alzheimer's Disease. Recent studies identified brevican as a meprin β substrate, and this study demonstrates that meprin α co‐expression enhances meprin β‐mediated brevican cleavage. Further, neurocan and RPTPζ were identified as novel meprin β substrates in an N‐terminomics analysis of meprin β transgenic mice,
Simon Kreiselmaier   +13 more
wiley   +1 more source

Structure and Activity of Class II Lanthipeptides From a Thermophilic Bacterium

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
Heterologous coexpression of the lanthipeptide synthetase TlaM from the thermophilic bacterium Thermoactinomyces sp. DSM 45891, with the precursor peptides TlaA1 and TlaA2 in Escherichia coli, resulted in the introduction of four thioether rings in both peptides.
Enleyona Weir   +2 more
wiley   +1 more source

Deciphering guanidine assimilation and riboswitch-based gene regulation in cyanobacteria for synthetic biology applications. [PDF]

open access: yesProc Natl Acad Sci U S A
Itzenhäuser MA   +12 more
europepmc   +1 more source

Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Building on the excellent review article by Dardonville and Rozas (2004), this paper summarizes the most representative ligands of imidazoline receptors (IR; I1, I2, and I3) and updates their pharmacological profiles. Although not exhaustive, it provides a solid starting point for understanding the significance of I2 IRs as promising therapeutic ...
Maria‐Eleni Kouridaki   +2 more
wiley   +1 more source

Steuerung der Rotation eines Guanidiniumkations durch Kation‐π‐Wechselwirkungen

open access: yesAngewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Ein Lanthanid‐π‐Container wurde für die Bindung eines Guanidiniumkations in dessen aromatischer Kavität mittels Kation‐π‐Wechselwirkungen verwendet. Röntgenkristallographie und Festkörper‐NMR‐Spektroskopie bei schneller Rotation um den magischen Winkel wurden verwendet, um die zugrundeliegenden Wirt‐Gast‐Interaktionen zu untersuchen.
Hannah Busch   +12 more
wiley   +1 more source

Controlling the Guanidinium Cation Rotation by Cation–π Interactions

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 29, 13 July 2026.
A lanthanide π‐container has been employed to trap a guanidinium cation inside the aromatic cavity by cation–π interactions. X‐ray crystallography and solid‐state nuclear magnetic resonance (NMR) spectroscopy at fast magic‐angle spinning (MAS) frequencies have been utilized to probe the underlying host–guest interactions.
Hannah Busch   +12 more
wiley   +1 more source

State‐of‐the‐Art and Synthetic Challenges for Hydrosilane Production

open access: yesChemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
The synthesis of hydrosilanes is currently energy intensive and their recycling is not considered. However, these compounds are important in many industrial fields but also for the valorization of oxygenated waste, towards a circular economy. This review compares the available synthetic routes and highlights the remaining challenges for the production ...
Gabriel Durin   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy