Results 141 to 150 of about 68,963 (231)

Research progress on application of guanidinoacetic acid in sheep production

Siliao yanjiu
Guanidinoacetic acid (GAA) is an important precursor of creatine synthesis in vertebrates, and is also a new nutritional feed additive. Due to its good cost performance and bioavailability, as well as its more stable characteristics than creatine ...
ZHANG Jian-sheng, HUANG Xin-yu, NAN Jing-dong, CHEN Guo-wang, HAO Cai-hong, ZHANG Bei, GUO Li-hong, ZHU Yuan-fang   +7 more
doaj  

Targeting DYRK1A with rationally designed pyrazine-guanidine hybrids for Alzheimer's disease: design, synthesis, and biological evaluation. [PDF]

RSC Adv
Khan S, Khan S, Khan S, Rahman MA, Rahman A, Reza A, Khurana S, Ashraf MZ, Islam A, Hoda N.   +9 more
europepmc   +1 more source

Constrictions and shear stress are key determinants of amyloidogenic light chain (AL) amyloidosis

The FEBS Journal, EarlyView.
In this study, we investigate how flow constrictions and shear stress trigger cardiac antibody light chain (AL) fibril formation and deposition. We mimic the mechanical forces exerted by the heart and the microvasculature network using a mini‐peristaltic pump setup and a grid‐type microchannel network, respectively.
Yuji Goto, Keiichi Yamaguchi, Kichitaro Nakajima, Ikuko Yumen, Ruiming He, Hirokazu Matsuda, Tetsuichi Wazawa, Takeharu Nagai, Nobuhiro Tsukada, Suguru Yamamoto, Johannes Buchner, Hirotsugu Ogi   +11 more
wiley   +1 more source

A Structure-Activity Relationship Study of Trypargine and Opacaline β-Carbolines. [PDF]

Mar Drugs
Chen D, Rouvier F, Brunel JM, Copp BR, Cadelis MM.   +4 more
europepmc   +1 more source

Synthesis Of New Morpholine Guanidine Urea Derivatives

, 2012
Anahtar Kelime: Üre, guanilüre, guanidin, 2-morpholinoetanamin, 1-(2-morpholinoetil)guanidinÜre türevlerinin doğal bileşik olması ve geniş bir biyolojik aktiviteye sahip olması araştırmacıların bu bileşiklere olan ilgisini arttırmıştır.
Danışman: Doç. Dr. Mustafa Zengin, Alkan, Fatih   +1 more
core  

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Lipophilic mono-guanidines <i>versus</i> mono-(thio)ureas: anion transport, lipid binding, and antibacterial activity. [PDF]

RSC Adv
De Silva Weerakonda Arachchige RD, Marshall SR, Gneid H, Busschaert N.   +3 more
europepmc   +1 more source

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

Periodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens, Cees Valkenburg, Fridus Van der Weijden   +2 more
wiley   +1 more source

Enhanced Solubility of Famotidine through Salification. [PDF]

Cryst Growth Des
Eilers JM, Seo P, Ma L, Kelley SP, Hutchins KM.   +4 more
europepmc   +1 more source

Sedentary ageing remodels the structure–function relationships that underlie calcium signalling at super‐resolution scales in the heart

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of calcium spark function and ryanodine receptor (RyR) structure within a sedentary model of ageing. Upon sympathetic stimulation from 1 µM isoprenaline a linear response to calcium spark morphology occurred, accompanied by a biphasic progression of RyR remodelling across age.
Miriam E. Hurley, David Conesa, Alan P. Benson, Michael A. Colman   +3 more
wiley   +1 more source