Results 171 to 180 of about 68,963 (231)

A rapid and accurate guanidine CEST imaging in ischemic stroke using a machine learning approach. [PDF]

open access: yesPhys Med Biol
Viswanathan M   +7 more
europepmc   +1 more source

A Machine Learning Approach That Measures Extracellular pH Within an In Vivo Tumor Model Using acidoCEST MRI

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
Machine learning models, particularly RFR (random forest regression), provide accurate and computationally efficient tumor pHe estimation from acidoCEST MRI without requiring auxiliary parametric maps. RFR achieved comparable performance to traditional Bloch fitting (RMSE: 0.020 vs.
Alia Khaled   +6 more
wiley   +1 more source

Engineering a protein homodimer from a heterodimer: A chimeric DBHS protein

open access: yesProtein Science, Volume 35, Issue 10, October 2026.
Abstract Drosophila behavior/human splicing (DBHS) proteins are involved at nearly every stage of the RNA lifecycle. There are three paralogues in mammals—SFPQ, NONO and PSPC1—which form both homodimer and heterodimers. It is likely that the non‐redundant and overlapping roles of the different DBHS paralogues emerge from their dynamic and combinatorial
Andrew C. Marshall   +5 more
wiley   +1 more source

Impact of Positively Charged Backbone Modifications on the Properties of Spherical Nucleic Acids

open access: yesSmall, Volume 22, Issue 55, 1 October 2026.
A synthesis of spherical nucleic acids (SNAs) featuring cationic backbone modifications is presented, together with an analysis of their emerging properties. Introducing positively charged guanidinium groups near the SNA surface enhances cellular uptake and offers a pathway toward more precise control over SNA internalization.
Katherine E. Bujold   +4 more
wiley   +1 more source

Modular Metalloprotein Nanowires With Semiconductor‐Scale Conductivity and Tunable Redox Behavior

open access: yesSmall Structures, Volume 7, Issue 10, October 2026.
Conductive protein nanowires are built by aligning three different metalloproteins along an ultrastable filament scaffold. The resulting micrometer‐length nanowires reach conductivities of 1.75 S cm−1. Redox behavior is set by the metalloprotein chosen, while conductivity is governed by the spacing the scaffold imposes, making both independently ...
Nga T. Lam   +3 more
wiley   +1 more source

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