A rapid and accurate guanidine CEST imaging in ischemic stroke using a machine learning approach. [PDF]
Viswanathan M +7 more
europepmc +1 more source
Machine learning models, particularly RFR (random forest regression), provide accurate and computationally efficient tumor pHe estimation from acidoCEST MRI without requiring auxiliary parametric maps. RFR achieved comparable performance to traditional Bloch fitting (RMSE: 0.020 vs.
Alia Khaled +6 more
wiley +1 more source
Structure- and Ligand-Based Discovery of Novel Non-Arginine-Based DDAH1 Inhibitors with Anti-Triple-Negative Breast Cancer Activity. [PDF]
Doman AJ +6 more
europepmc +1 more source
Engineering a protein homodimer from a heterodimer: A chimeric DBHS protein
Abstract Drosophila behavior/human splicing (DBHS) proteins are involved at nearly every stage of the RNA lifecycle. There are three paralogues in mammals—SFPQ, NONO and PSPC1—which form both homodimer and heterodimers. It is likely that the non‐redundant and overlapping roles of the different DBHS paralogues emerge from their dynamic and combinatorial
Andrew C. Marshall +5 more
wiley +1 more source
Organocatalytically-Tuned In Situ Formed Alginate Hydrogel Enables Sustained Therapeutic Release. [PDF]
Das N, Kadam A, Jaiswal AK, Maity C.
europepmc +1 more source
Impact of Positively Charged Backbone Modifications on the Properties of Spherical Nucleic Acids
A synthesis of spherical nucleic acids (SNAs) featuring cationic backbone modifications is presented, together with an analysis of their emerging properties. Introducing positively charged guanidinium groups near the SNA surface enhances cellular uptake and offers a pathway toward more precise control over SNA internalization.
Katherine E. Bujold +4 more
wiley +1 more source
Corrigendum to: "HPLC-MS/MS Phenolic Profiling, Antioxidant, Antiaging Activities, and Molecular Docking Studies for Deverra tortuosa and Deverra triradiata Roots and Flowers". [PDF]
europepmc +1 more source
Distinct hyaluronan content and hierarchical organization of collagen-elastic fiber assemblies in subcutaneous fascia. [PDF]
Maeda N, Togashi K, Shin Y, Imamura Y.
europepmc +1 more source
Modular Metalloprotein Nanowires With Semiconductor‐Scale Conductivity and Tunable Redox Behavior
Conductive protein nanowires are built by aligning three different metalloproteins along an ultrastable filament scaffold. The resulting micrometer‐length nanowires reach conductivities of 1.75 S cm−1. Redox behavior is set by the metalloprotein chosen, while conductivity is governed by the spacing the scaffold imposes, making both independently ...
Nga T. Lam +3 more
wiley +1 more source
Synergistic diselenide/guanidine catalyzed dehydrophosphorylation of 2-nitrobenzhydrols to access C-stereogenic phosphinates. [PDF]
Gong JY +6 more
europepmc +1 more source

