Results 181 to 190 of about 68,963 (231)

Pressure‐Induced Changes in Intracellular pH Facilitate the Myogenic Response of Rat Small Tail Arteries

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim The myogenic response contributes considerably to blood flow autoregulation. Intracellular pH (pHi) has a substantial impact on small artery contractility. However, the role of putative pHi changes during myogenic constriction is unknown.
Ulrike Krien, Rudolf Schubert
wiley   +1 more source

Comprehensive Reinvestigation of Carbodiimide Guanylation: HCl-Initiated Access to Tri- and Tetrasubstituted Guanidines. [PDF]

ACS Omega
Vlk L, Pauk K, Samsonov MA, Růžičková Z, Chlupatý T, Růžička A.   +5 more
europepmc   +1 more source

Triazole‐Linked Pyrimidine Nucleoside Dimers: Design, Synthesis, and Applications in Medicinal and Nucleic Acid Chemistry. Part IV

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
A series of 18 pyrimidine nucleoside dimers analogues with a short 1,4‐disubstituted 1,2,3‐triazole linkage were synthesized using a click chemistry approach (CuAAC). Analysis of the obtained products was conducted utilizing 1D/2D NMR spectroscopy (1H, 13C, 19F, 15N, and 29Si), mass spectrometry (ESI‐MS), and high‐performance liquid chromatography ...
Dagmara Baraniak, Dariusz Wawrzyniak, Daniel Baranowski   +2 more
wiley   +1 more source

Scalable Production of a <i>De Novo</i> SARS-CoV-2 Antiviral Miniprotein in <i>Escherichia coli</i>. [PDF]

Pharmaceutics
Shin J, Kim EM, Jang JH, Jee SW, Kim SH, Yu S, Yoon M, Craig D, Swoyer R, Patel S, Alamuri P, Price A, Ravichandran R, Carter L, Pallerla S.   +14 more
europepmc   +1 more source

Ovarian Cancer‐Associated Ascites Accumulates NK Lymphocytes Displaying a Transcriptomic Profile Consistent With the Immature/Secretory CD56bright Subtype

Immunology &Cell Biology, Volume 104, Issue 9, Page 896-905, October 2026.
NK cells present in EOC‐associated ascites retain elements of the conventional NK cell program while displaying a transcriptional profile distinct from peripheral blood NK cells. This profile encompasses biological programs usually associated with the CD56bright NK cell functions, which is consistent with transcriptional remodeling rather than complete
Caroline Natânia de Souza‐Araújo, Glenerson Baptista, Gabriela Rapozo Guimarães, Raissa Carolina Alves da Silva, Adriana Yoshida, Cláudia Rodrigues Tonetti, José Andrés Yunes, Daniela Maira Cardoso, Sophie Derchain, Mariana Boroni, Fernando Guimarães   +10 more
wiley   +1 more source

Electrodeficient Diborane (4) Converted into an Extraordinary Proton Sponge. [PDF]

J Phys Chem A
Yáñez M, Montero-Campillo MM, Mó O, Alkorta I.   +3 more
europepmc   +1 more source

Remediation of chronic ammonia effects in common carp by dietary thymol supplementation

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract Chronic ammonia toxicity represents a major challenge in intensive aquaculture, often leading to impaired growth and physiological distress. This study evaluated the efficacy of dietary thymol supplementation in mitigating the deleterious effects of chronic ammonia exposure in common carp, Cyprinus carpio. Fish (initial weight: 10.41 ± 0.23 g)
Morteza Yousefi, Seyed Hossein Hoseinifar, Evgeny Vladimirovich Kulikov, Arfenia Semenovna Karamian, Aleksandr Vladimirovich Tkachev, Kristina Viktorovna Shepeleva, Seyyed Morteza Hoseini   +6 more
wiley   +1 more source

Hydrochlorides, hydrates, hydronitrate, and an unanticipated hydrolysis product of famotidine. [PDF]

Acta Crystallogr C Struct Chem
Weaver MC, Oliver AG, Barstis TLO.
europepmc   +1 more source

A Blood–Brain Barrier‐Permeable Guanylhydrazone Analogue of the ASIC3 Activator GMQ Inhibits Human Glioblastoma Stem Cell Growth In Vitro

ChemMedChem, Volume 21, Issue 18, 28 September 2026.
The acid‐sensing ion channel 3 (ASIC3), physiologically located in the peripheral nervous system, was found in stem cells of CNS‐located glioblastoma multiforme (GBM CSCs); its chronic activation in the CNS kills dysfunctional GBM CSCs with no effect on ASIC3‐lacking CNS tissues.
Leonardo Maiorana, Nicoletta Collura, Andrea Gotti, Giulia De Leonardis, Greta Donati, Alice Maiocchi, Luciana Marinelli, Andrea Menegon, Pierfausto Seneci   +8 more
wiley   +1 more source

RNA-binding landscape of amiloride: large-scale profiling and structural basis of U-U mismatch recognition. [PDF]

RSC Chem Biol
Tsuzuki K, Onizuka K, Okada M, Nagasawa R, Miyashita E, Komatsu KR, Saito H, Kondo J, Nagatsugi F.   +8 more
europepmc   +1 more source