Results 231 to 240 of about 320,673 (337)

Regioselectivity and physical nature of the interactions between (methyl)guanine with HCl and CH3OH [PDF]

Detila Diyavanga, Bienfait Kabuyaya Isamura, Mireille K. Bilonda, Frédéric Kafwaya Kahenga, Mayaliwa Muzomwe, Jules Tshishimbi Muya   +5 more
openalex   +1 more source

The Graphene Oxide Memristive DNA Sensor for Taxonomic Fingerprint

Macromolecular Materials and Engineering, EarlyView.
A graphene oxide–based memristive DNA sensor enables rapid, label‐free quantification of nucleotide base composition across 37%–55% GC with strong linear calibration. Delivering results within 2–5 min, the platform combines high sensitivity with minimal sample preparation, offering a practical tool for point‐of‐care diagnostics, genetic fingerprinting,
Konstantin G. Nikolaev, Jia Hui Bong, Siyu Chen, Kostya S. Novoselov, Daria V. Andreeva   +4 more
wiley   +1 more source

Development of CPE/ssDNA-Based Electrochemical Sensor for the Detection of Leucine to Assess Soil Health. [PDF]

Biosensors (Basel)
Girousi S, Banti Z, Karastogianni S, Papi R, Ozkan Ariksoysal D, Golia EE.   +5 more
europepmc   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Platinum Meets Pyridine: Affinity Studies of Pyridinecarboxylic Acids and Nicotinamide for Platinum-Based Drugs. [PDF]

Int J Mol Sci
Szefler B, Szupryczyński K, Czeleń P.
europepmc   +1 more source

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source

Guanine and pregnenolone sulfate are associated with incident type 2 diabetes in two independent populations. [PDF]

Front Endocrinol (Lausanne)
Barranco-Altirriba M, Granado-Casas M, Yanes O, Capellades J, Junza A, Franch-Nadal J, Vendrell J, Llauradó G, Valdés S, García-Escobar E, Bermúdez-López M, Valdivielso JM, López-Lifante VM, Herrero-Alonso C, Falguera M, Vilanova MB, Arteaga I, Torán-Monserrat P, Perera-Lluna A, Castelblanco E, Mauricio D.   +20 more
europepmc   +1 more source

Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex

, 2004
Christina Kiel, Tzvia Selzer, Yoav D. Shaul, Gideon Schreiber, Christian Herrmann   +4 more
openalex   +1 more source

Interplay Between Sex and Cytosine‐Adenine‐Guanine‐Age Product Score in Huntington's Disease: Clinical and Neuroimaging Perspectives

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a cytosine‐adenine‐guanine (CAG) repeat expansion in the huntingtin gene. The disease exhibits sex‐related differences in symptomatology and disease progression, but the effect on brain structural biomarkers and the interaction between sex and CAG‐age ...
Jingwen Yao, Grayson Feng, Guowen Shao, Zexi Wang, Adys Mendizabal, Donatello Telesca, Kaiying Fang, Lola Ibragimova, Juwairia Shoaib, Melanie A. Morrison, Janine M. Lupo   +10 more
wiley   +1 more source

Discriminatory Residues in Ras and Rap for Guanine Nucleotide Exchange Factor Recognition

, 1999
N van den Berghe, Robbert H. Cool, Alfred Wittinghofer   +2 more
openalex   +1 more source