Results 301 to 310 of about 320,673 (337)

Conserved guanine-guanine stacking in tetraplex and duplex DNA

European Biophysics Journal, 2001
Using a series of suitably chosen oligonucleotides, we demonstrate that the DNA duplex of d(CCCCGGGG) provides an almost identical CD spectrum as the parallel-stranded tetraplex of d(GGGG). The CD spectra are very sensitive to base stacking in DNA so that the above observation indicates that guanine-guanine stacking is essentially the same within the ...
J, Kypr, M, Fialová, J, Chládková, M, Tůmová, M, Vorlícková   +4 more
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Radical–Radical Interactions among Oxidized Guanine Bases Including Guanine Radical Cation and Dehydrogenated Guanine Radicals

The Journal of Physical Chemistry B, 2013
We present here a theoretical investigation of the structural and electronic properties of di-ionized GG base pairs (G(•+)G(•+),G(-H1)(•)G(•+), and G(-H1)(•)G(-H1)(•)) consisting of the guanine cation radical (G(•+)) and/or dehydrogenated guanine radical (G(-H1)(•)) using density functional theory calculations. Different coupling modes (Watson-Crick/WC,
Jing, Zhao, Mei, Wang, Hongfang, Yang, Meng, Zhang, Ping, Liu, Yuxiang, Bu   +5 more
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Guanine-uracil base-pairing

Biochemical and Biophysical Research Communications, 1972
Abstract The interaction of guanosine and 2′-deoxyuridine has been examined by high resolution pmr spectroscopy in DMSO-water mixtures. Evidence is presented for G-U base-pairing in solvent mixtures where the water content is sufficiently high. Downfield shifts were observed for the N(1)-H, NH2 protons of G and the N(3)-H proton of U, suggesting that
S I, Chan, G C, Lee, C F, Schmidt, G P, Kreishman   +3 more
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New guanine deaminase inhibito RS

Pharmacological Research Communications, 1984
2-Aryl/alkyl-3-(5'-carboxamido-imidazol-4'-yl)-quinazolin-4-(3H)-o nes have been reported as Guanine deaminase inhibitors. These compounds were prepared from 4-amino-5-imidazol-carboxamide and suitable 2-aryl/alkyl-benzoxazin-4-ones. Compounds were characterized by their m.ps., elemental analyses and I. R. spectra.
A K, Saxena, S, Ahmad, K, Shanker, K, Kishor   +3 more
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Metabolism of Guanine and Guanine Nucleotides in Primary Rat Cardiomyocyte Cultures

Biochemical and Molecular Medicine, 1995
The metabolic fate of labeled guanine and of prelabeled guanine nucleotides (GuRN) was studied in cultured rat cardiomyocytes. Special attention was given to guanine salvage in comparison to degradation; to the contribution of GuRN to adenine nucleotides (AdRN); to the fluxes from GMP to IMP and from IMP to GMP; and to the degradation pathways of GuRN.
E, Zoref-Shani, C, Shirin, Y, Sidi, Y, Bromberg, O, Sperling   +4 more
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Metabolism of Guanine and Guanine Nucleotides in Primary Rat Neuronal Cultures

Journal of Neurochemistry, 1992
Abstract: The metabolic fate of guanine and of guanine ribonucleotides (GuRNs) in cultured rat neurons was studied using labeled guanine. 8‐Aminoguanosine (8‐AGuo), an inhibitor of purine nucleoside phosphorylase, was used to clarify the pathways of GMP degradation, and mycophenolic acid, an inhibitor of IMP dehydrogenase, was used to assess the flux ...
S, Brosh, O, Sperling, E, Dantziger, Y, Sidi   +3 more
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Pentaammineruthenium-guanine complexes

Journal of the American Chemical Society, 1974
The synthesis of several pentaammineruthenium(I1 and 111)-guanine complexes is reported, in which the metal is believed to be bound to Ni. The Ru(II1) compounds exhibit a broad low energy guanine-to-metal chargetransfer absorption, while the Ru(1I) complexes show a metal-to-ligand charge transfer in the ultraviolet.
Michael J. Clarke, Henry Taube
openaire   +1 more source

Guanine Uptake by Human Erythrocytes

1991
It has been clearly established that mature human erythrocytes cannot synthesize de novo purines (1); consequently the turnover of purine nucleotides in red cells must result from the continual entry and release of purines. Hypoxanthine and adenine uptake by human erythrocytes has been studied in our laboratories (2–4).
SPOTO, Giuseppe, QUARATINO CP, GIACOMELLO A.   +2 more
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LINGCOD MUSCLE GUANINE DEAMINASE

Canadian Journal of Biochemistry, 1966
The enzyme guanine deaminase was found in lingcod muscle and a study of its properties carried out. In the crude state, two pH optima were found, one of which was lost on purification. Of several guanine analogues tested, only 8-azaguanine was deaminated by the enzyme. A number of compounds were tested as inhibitors. No cofactors were required.
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Photodynamic degradation of guanine

Biochemical and Biophysical Research Communications, 1964
J S, Sussenbach, W, Berends
openaire   +3 more sources