Results 71 to 80 of about 316,659 (284)

Thermodynamic and kinetic insights into stop codon recognition by release factor 1. [PDF]

open access: yes, 2014
Stop codon recognition is a crucial event during translation termination and is performed by class I release factors (RF1 and RF2 in bacterial cells). Recent crystal structures showed that stop codon recognition is achieved mainly through a network of ...
Joseph, Simpson   +2 more
core  

Dual-tip-enhanced ultrafast CARS nanoscopy [PDF]

open access: yes, 2013
Coherent anti-Stokes Raman scattering (CARS) and, in particular, femtosecond adaptive spectroscopic techniques (FAST CARS) have been successfully used for molecular spectroscopy and microscopic imaging.
  +15 more
core   +3 more sources

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

open access: yesAdvanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim   +16 more
wiley   +1 more source

Inverse Virtual Screening, Recombinant Expression, and Activity Characterization of Purine Degrading Enzymes

open access: yesShipin gongye ke-ji
To develop a novel purine degrading enzyme that can be used in the food industry, this study aimed to screen an enzyme with potential purine degradation activity using inverse virtual screening technology and molecular docking technology, clone express ...
Yu LIU   +3 more
doaj   +1 more source

Direct determination of guanine in Aciclovir Dispersible Tablets solution by acylpyrazolone modified glassy carbon electrode

open access: yesReviews in Analytical Chemistry, 2011
In this article, the investigation of electrochemical determination of guanine(GU) by 1-phenyl-3-methyl-4-(2-furoyl)-5-pyrazolone (HPMαFP) modified glassy carbon electrode (HPMαFP/GCE) in Aciclovir Dispersible Tablets solution was reported.
Li Xueli, Li Jinzhou
doaj   +1 more source

Biological and Biologically Inspired Functional Nanostructures: Insights into Structural, Optical, Thermal, and Sensing Applications

open access: yesAdvanced Materials, EarlyView.
Biological and biologically‐inspired functional nanostructures with structural, thermal, optical, and sensing applications are reviewed. The role of nanoscale features in biological materials on performance is described, and their blueprints are used for bio‐inspired nanomaterials, synthesized using advanced techniques (i.e., photolithography, bio ...
Chao Hsuan (Joseph) Sung   +15 more
wiley   +1 more source

Common Mitochondrial DNA Mutations Generated through DNA-Mediated Charge Transport [PDF]

open access: yes, 2009
Mutation sites that arise in human mitochondrial DNA as a result of oxidation by a rhodium photooxidant have been identified. HeLa cells were incubated with [Rh(phi)2bpy]Cl3 (phi is 9,10-phenanthrenequinone diimine), an intercalating photooxidant, to ...
Barton, Jacqueline K.   +2 more
core   +2 more sources

The First Review on Nano‐Agricultural Applications of MXene and MBene‐Based Materials for Plant‐Immunoengineering, Controlled Protection, and Inducing Biostimulation Mechanisms

open access: yesAdvanced Materials, EarlyView.
MXene and MBene nanomaterials show significant potential in addressing critical challenges in biomedicine, applied biology, agriculture, and the environment. From a nano‐agricultural perspective, this relatively young field has witnessed emerging advances towards applications for plant‐immunoengineering, biostimulation, and controlled delivery ...
Alireza Rafieerad   +3 more
wiley   +1 more source

An Electrochemical DNA Biosensor for Carcinogenicity of Anticancer Compounds Based on Competition between Methylene Blue and Oligonucleotides

open access: yesSensors, 2019
A toxicity electrochemical DNA biosensor has been constructed for the detection of carcinogens using 24 base guanine DNA rich single stranded DNA, and methylene blue (MB) as the electroactive indicator.
Nor Diyana Md. Sani   +7 more
doaj   +1 more source

High-Resolution Three-Dimensional NMR Structure Of The KRAS Proto-Oncogene Promoter Reveals Key Features Of A G-Quadruplex Involved In Transcriptional Regulation [PDF]

open access: yes, 2017
Non-canonical base pairing within guanine-rich DNA and RNA sequences can produce G-quartets, whose stacking leads to the formation of a G-quadruplex (G4).
Ivashchenko, S.   +5 more
core   +2 more sources

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