Results 231 to 240 of about 84,425 (312)
Abstract The melanocortin‐4 receptor (MC4R) is a G protein‐coupled receptor with an essential role in appetite suppression and energy homeostasis. Genetic mutations in the receptor and components of its signalling pathway that cause obesity in humans, dogs and rodent models have revealed important insights into how the receptor signals and what ...
Aqfan Jamaluddin +3 more
wiley +1 more source
Similarities in Function and Gene Structure of Cytohesin-4 and Cytohesin-1, Guanine Nucleotide-exchange Proteins for ADP-ribosylation Factors [PDF]
Masahito Ogasawara +8 more
openalex +1 more source
Significance Statement This review synthesizes current knowledge of plant hormone transporters across five major protein superfamilies. It links structural classification to transport mechanism and substrate specificity and demonstrates that this structural perspective provides a predictive framework for understanding substrate scope, selectivity ...
Bjørn Lildal Amsinck +4 more
wiley +1 more source
Vav Guanine nucleotide exchange factors regulate atherosclerotic lesion development in mice. [PDF]
Rahaman SO, Li W, Silverstein RL.
europepmc +1 more source
SUMMARY Plants face constant environmental changes and must integrate external and internal cues to coordinate growth, development, reproduction, and stress responses. A major strategy is perception at the cell surface via a large, diverse network of receptors.
Bruno Pok Man Ngou +2 more
wiley +1 more source
Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang +7 more
wiley +1 more source

