Chemistry – A European Journal, EarlyView.First report on 7‐membered cyclic nucleotides, 2',3'‐cNTDPs, obtained from all‐natural free ribonucleosides in robust, step‐economic synthesis involving instantaneous and regio‐selective reaction. DFT calculations confirmed the feasibility of 7‐membered cyclic nucleotide formation and deciphered the basis for regioselectivity.
Sveta Liberman +4 more
wiley +1 more source
Identification of guanosine triphosphate as the 5'-terminus of RNA from bacteriophage Q-beta and R23. [PDF]
, 1968 M. Watanabe, J. T. August
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The Ascent of Supramolecular Polymers and Gels in Asymmetric Catalysis
Chemistry – A European Journal, Accepted Article.Supramolecular polymers and gels, formed by the spontaneous assemblies of small molecules through various types of non‐covalent interactions, are attractive materials for many applications. Their modularity also offers many opportunities in asymmetric catalysis, that have been tackled in the last two decades and more intensively in the last one.
Ran Chen +2 more
wiley +1 more source
Production of Guanosine-5′-Monophosphate and Inosine-5′-Monophosphate by Fermentation [PDF]
, 1966 A. L. Demain +4 more
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Tailored Watson–Crick Pairing Partners for Xanthosine in RNA
Chemistry – A European Journal, Accepted Article.The deamination of guanosine nucleobases results in the formation of xanthosine (X)‐containing RNA. This process formally resembles adenine deamination (A‐to‐I editing). The biological significance and basic chemical consequences of X‐modified RNA are poorly understood.
Ronald Micura +5 more
wiley +1 more source
Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
British Journal of Pharmacology, EarlyView., 2023 Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay
Cytoskeleton, EarlyView.ABSTRACT Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternative splicing of a neural‐specific microexon in DAAM1 in modulating actin's role in synaptic processes.
Patryk Poliński +2 more
wiley +1 more source
Guanine-Based Purines as an Innovative Target to Treat Major Depressive Disorder
Frontiers in Pharmacology, 2021 Roberto F. Almeida +7 more
doaj +1 more source
Vibrational Partition Functions from Bond Order and Populations Relationships
ChemPhysChem, EarlyView.A new computational model is presented that predicts vibrational partition functions using bond orders and populations relationships (QBOP). This model demonstrates that thermochemical energy contributions can be reasonably approximated based on well‐conditioned orbital populations without the need for a costly Hessian calculation.
Barbaro Zulueta, John A. Keith
wiley +1 more source
Electrochemical and Spectroscopic Studies of Interactions of Mn(III) Complexes with Nucleic Bases and Nucleosides [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1995 The complexes of Mn(OAc)3 and/or Mn(acac)3 with nucleic bases and nucleosides (adenine, guanine, xanthine, adenosine and guanosine) have been synthesized in nonaqueous solution.
Davar Mohammadi Boghai +2 more
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