Results 131 to 140 of about 231,754 (311)
Phylogeny of conserved adenines in linkers of Group-I introns [PDF]
, 2009 We have analyzed the linkers in group-I introns, a characteristic region that is crucial to the folding and splicing process of the folded RNA, in seventy sequences spreading across r-RNA, t-RNA and organelle genes from various organisms including algae,
Chandrasekhar Kesavan, Natarajan Ganesan
core +1 more source
Simple Guanosine—Amino Acid Hybrids as Low Molecular Weight Hydrogelators
Chemistry – A European Journal, EarlyView.Unexplored guanosine‐amino acid derivatives act as low molecular weight hydrogelators. Gelation is triggered by K+ ions and pH changes and relies on G‐quadruplex formation. Small changes in the amino acid structure have a strong impact on the mechanical properties of the gels.
Silvia Pieraccini +6 more
wiley +1 more source
Association of NGF receptors with membrane rafts in PC12 cells : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 2001 Nerve Growth Factor (NGF) signal transduction is involved in the survival, differentiation and maintenance of neurons through the receptors TrkA and p75NTR. These receptors activate downstream protein kinase cascades that regulate cell survival.
Clements, Shona Marie
core
Cytoskeleton, EarlyView.ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen +2 more
wiley +1 more source
Guanosine diphosphate glucose and guanosine diphosphate fructose from Eremothecium ashbyii [PDF]
Biochemical Journal, 1959 H G, PONTIS, A L, JAMES, J, BADDILEY
openaire +3 more sources
5\u27-Terminal nucleotide variations in human cytoplasmic tRNAHisGUG and its 5\u27-halves. [PDF]
, 2017 Transfer RNAs (tRNAs) are fundamental adapter components of translational machinery. tRNAs can further serve as a source of tRNA-derived noncoding RNAs that play important roles in various biological processes beyond translation.
Kirino, Yohei, Shigematsu, Megumi
core +1 more source
Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib
Clinical Pharmacology &Therapeutics, EarlyView.Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi +5 more
wiley +1 more source
Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?
Clinical Pharmacology &Therapeutics, EarlyView.Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu +5 more
wiley +1 more source
BMC MicrobiologyThe overproduction of uric acid, driven by its key precursors (inosine and guanosine), leads to hyperuricemia, a metabolic disorder associated with severe complications such as gout and renal dysfunction.
Xiaoyu Cao +3 more
doaj +1 more source