ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited.
Jung‐Hoon Kim, Yongtaek Oh, Suin Cho
wiley +1 more source
Structure and Function of Archaeal SRP54 Protein Mutants Associated with Human Severe Congenital Neutropenia. [PDF]
Yang M +6 more
europepmc +1 more source
Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin +7 more
wiley +1 more source
Arabidopsis nanopore direct RNA sequencing data for mutants in splicing, polyadenylation, and m6A methylation. [PDF]
Gumińska N +8 more
europepmc +1 more source
Multi‐State Resistance in Microtubule‐Templated Gold Nanowires
The scaling limits of CMOS transistors require alternative, dynamically reconfigurable nanoscale devices. This study demonstrates the multi‐state resistance in pure gold nanowires templated by microtubules. Continuous nanowires with local inhomogeneities enable electromigration‐driven, multistate resistance modulation under voltage pulses, while ...
Borja Rodriguez‐Barea +5 more
wiley +1 more source
Characterization of a Purine Nucleoside Phosphorylase From Colwellia sp. WH041 for Multienzyme Synthesis of Nucleoside Analogs. [PDF]
Wang S +6 more
europepmc +1 more source
Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu +7 more
wiley +1 more source
The guanosine nucleotide analog bemnifosbuvir inhibits hepatitis E virus infection in cell and organoid models. [PDF]
Liu K +6 more
europepmc +1 more source
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni +10 more
wiley +1 more source
Guanosine contributes to rapid purinergic regulation of dopamine during ischemia. [PDF]
Weese-Myers ME, Hassan ASA, Ross AE.
europepmc +1 more source

