Results 231 to 240 of about 225,684 (400)

Ferroptosis in Pneumoconiosis: From Molecular and Cellular Mechanisms to Therapeutic Strategies

Med Research, EarlyView.
Targeting lung various cells to alleviate pneumoconiosis by suppressing ferroptosis. AAV9‐HGF, adeno‐associated virus‐hepatocyte growth factor; DFP, deferiprone; DHQ, dihydroquercetin; Fer‐1, ferrostatin‐1; IL‐1β, interleukin‐1β; NMN, nicotinamide mononucleotide; sh‐SLC39A14, shRNA targeting solute carrier family 39 member 14; si‐OC‐STAMP, siRNA ...
Mengli Yan, Jing Zhang, Gaili Ji, Xiaobin Fang, Chunheng Mo   +4 more
wiley   +1 more source

Conquering 2-aminopurine's deficiencies: highly emissive isomorphic guanosine surrogate faithfully monitors guanosine conformation and dynamics in DNA.

Journal of the American Chemical Society, 2015
M. Sholokh, Rajhans Sharma, Dongwon Shin, R. Das, O. Zaporozhets, Y. Tor, Y. Mély   +6 more
semanticscholar   +1 more source

Cross-tissue coordination between SLC nucleoside transporters regulates reproduction in Caenorhabditis elegans. [PDF]

PLoS Genet
Guan Y, Yu Y, Gao SM, Ding L, Zhao Q, Wang MC.   +5 more
europepmc   +1 more source

Guanosine 3':5'-monophosphate-dependent protein kinase from silkworm, properties of a catalytic fragment obtained by limited proteolysis.

, 1976
Masatoshi Inoue, Akira Kishimoto, Yoshimi Takai, Yasutomi Nishizuka   +3 more
openalex   +1 more source

Bioregulation of lysosomal enzyme secretion from human neutrophils: roles of guanosine 3':5'-monophosphate and calcium in stimulus-secretion coupling. [PDF]

, 1975
Robert J. Smith, Louis J. Ignarro
openalex   +1 more source

Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.

Proceedings of the National Academy of Sciences of the United States of America, 1977
W. Arnold, C. K. Mittal, S. Katsuki, F. Murad   +3 more
semanticscholar   +1 more source

Early‐Onset Movement Disorder Syndrome Caused by Biallelic Variants in PDE1B Encoding Phosphodiesterase 1B

Movement Disorders, EarlyView.
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg, Noam Hadar, Eyal Kristal, Nicola Y. Roberts, Vadim Dolgin, Ilana Aminov, Amit Safran, Nadav Agam, Matan Jean, Ofek Freund, Eamonn G. Sheridan, James A. Poulter, Michelle L. Thompson, Yusra Algoos, Salma Al‐Qahtani, Lama AlAbdi, Sateesh Maddirevula, Verity Hartill, Henry Houlden, Reza Maroofian, Amit Nahum, Ohad S. Birk   +21 more
wiley   +1 more source

Landscape of targets within nucleoside metabolism for the modification of immune responses. [PDF]

Front Oncol
Dunderdale EM, Abt ER.
europepmc   +1 more source

A new nucleotide involved in the stringent response in Escherichia coli. Guanosine 5‘-diphosphate-3‘-monophosphate.

, 1979
C C Pao, Jonathan Gallant
openalex   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source