Variations in cyclic adenosine 3â²,5â²-monophosphate and cyclic guanosine 3â²,5â²-monophosphate in antibiotic producing strains ofStreptomyces hygroscopicus [PDF]
Dietrich Gersch +3 more
openalex +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu +4 more
wiley +1 more source
Crystal structures reveal the distinct features of the 2'-dG-III riboswitch in the purine riboswitch family. [PDF]
Chen K +7 more
europepmc +1 more source
LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang +12 more
wiley +1 more source
In vitro quality of whole blood-derived red cell concentrates collected, processed and stored in a blood bag set plasticized with di (2-ethylhexyl) terephthalate. [PDF]
Stephenson T +7 more
europepmc +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
A disubstituted aniline probe for enhanced peroxidase-based proximal protein labelling. [PDF]
Kaewsapsak P +15 more
europepmc +1 more source
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Guanine Crystal Formation at Physiological pH. [PDF]
Tah Roy B +8 more
europepmc +1 more source

