Results 241 to 250 of about 194,604 (252)

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.

Science, 1998
Mitogen stimulation of cytoskeletal changes and c-jun amino-terminal kinases is mediated by Rac small guanine nucleotide-binding proteins. Vav, a guanosine diphosphate (GDP)-guanosine triphosphate (GTP) exchange factor for Rac that stimulates the ...
Jaewon Han, K. Luby‐Phelps, B. Das, Xiaodong Shu, Yi Xia, R. Mosteller, U. Krishna, J. Falck, Michael A. White, D. Broek   +9 more
semanticscholar   +1 more source

Enhancing the Mechanical Properties of Guanosine-Based Supramolecular Hydrogels with Guanosine-Containing Polymers

, 2014
We demonstrate that multivalent, polymeric 8-methoxyguanosine derivatives based on poly(dimethylacrylamide) can enhance the mechanical properties of the low molecular weight hydrogelator 8-methoxy-2′,3′,5′-tri-O-acetylguanosine at biologically relevant ...
Amanda E. Way, Angie B. Korpusik, T. Dorsey, L. Buerkle, H. V. Recum, S. Rowan   +5 more
semanticscholar   +1 more source

Preventive effects of guanosine on intestinal inflammation in 2, 4-dinitrobenzene sulfonic acid (DNBS)-induced colitis in rats

InflammoPharmacology, 2018
M. Zizzo, G. Caldara, A. Bellanca, D. Nuzzo, M. Di Carlo, R. Serio   +5 more
semanticscholar   +1 more source

Guanosine Protects Against Traumatic Brain Injury-Induced Functional Impairments and Neuronal Loss by Modulating Excitotoxicity, Mitochondrial Dysfunction, and Inflammation

Molecular Neurobiology, 2016
R. Gerbatin, G. Cassol, Fernando Dobrachinski, A. P. O. Ferreira, C. Quines, Iuri D. Della Pace, G. L. Busanello, J. Gutierres, C. W. Nogueira, Mauro S. Oliveira, F. Soares, V. Morsch, M. Fighera, L. Royes   +13 more
semanticscholar   +1 more source

Guanosine Prevents Anhedonic-Like Behavior and Impairment in Hippocampal Glutamate Transport Following Amyloid-β1–40 Administration in Mice

Molecular Neurobiology, 2016
D. Lanznaster, J. M. Mack, Victor Coelho, Marcelo Ganzella, R. F. Almeida, T. Dal-Cim, G. Hansel, E. Zimmer, D. Souza, R. Prediger, C. Tasca   +10 more
semanticscholar   +1 more source

The antidepressant‐like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation

European Journal of Neuroscience, 2016
L. Bettio, V. B. Neis, F. L. Pazini, P. Brocardo, A. Patten, J. Gil-Mohapel, B. Christie, A. Rodrigues   +7 more
semanticscholar   +1 more source

Decreased levels of guanosine 3′, 5′‐monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease

Neuropathology and Applied Neurobiology, 2015
A. Ugarte, F. Gil-Bea, C. García‐Barroso, A. Cedazo-Mínguez, M. Ramírez, R. Franco, A. García-Osta, J. Oyarzábal, M. Cuadrado‐Tejedor   +8 more
semanticscholar   +1 more source

Guanosine Anxiolytic-Like Effect Involves Adenosinergic and Glutamatergic Neurotransmitter Systems

Molecular Neurobiology, 2015
R. F. Almeida, Daniel Diniz Comasseto, D. Ramos, G. Hansel, E. Zimmer, S. Loureiro, Marcelo Ganzella, D. Souza   +7 more
semanticscholar   +1 more source

Guanosine protects C6 astroglial cells against azide‐induced oxidative damage: a putative role of heme oxygenase 1

Journal of Neurochemistry, 2014
André Quincozes-Santos, L. Bobermin, D. G. Souza, Bruna Bellaver, C. Gonçalves, D. O. Souza   +5 more
semanticscholar   +1 more source

Guanosine Protects Against Cortical Focal Ischemia. Involvement of Inflammatory Response

Molecular Neurobiology, 2014
G. Hansel, A. Tonon, F. Guella, L. Pettenuzzo, T. Duarte, M. Duarte, J. Oses, M. Achaval, D. Souza   +8 more
semanticscholar   +1 more source