Results 261 to 270 of about 201,939 (380)
The Guanosine-Adenosine Interaction Exists In Vivo
E. Jackson, Z. Mi
semanticscholar +1 more source
PI5P4K inhibitors: promising opportunities and challenges
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi+16 more
wiley +1 more source
Purine nucleoside phosphorylase dominates Influenza A virus replication and host hyperinflammation through purine salvage. [PDF]
Yue Y+19 more
europepmc +1 more source
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres+10 more
wiley +1 more source
Discovery of reversing enzymes for RNA ADP-ribosylation reveals a possible defence module against toxic attack. [PDF]
Lu Y+8 more
europepmc +1 more source
Transforming mutations of RAC guanosine triphosphatases in human cancers
Masahito Kawazu+16 more
semanticscholar +1 more source
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley +1 more source
Self-Regulating Hydrogel with Reversible Optical Activity in Its Gel-to-Gel Transformation. [PDF]
Li J+13 more
europepmc +1 more source