Results 121 to 124 of about 37,457,458 (124)

Cholesterol-Dependent Association of Caveolin-1 with the Transducin α Subunit in Bovine Photoreceptor Rod Outer Segments:  Disruption by Cyclodextrin and Guanosine 5‘-O-(3-Thiotriphosphate)

Biochemistry, 2003
Evidence suggests that caveolins, 21-24 kDa cholesterol-binding proteins that generally reside in specialized detergent-resistant membrane microdomains, act as signaling scaffolds. Detergent-resistant membranes isolated from rod outer segments (ROS) have been previously shown to contain the photoreceptor G-protein, transducin.
Michael H, Elliott, Steven J, Fliesler, Abboud J, Ghalayini   +2 more
openaire   +2 more sources

2-[125I]iodomelatonin binding sites in the quail liver: characterization and the effect of guanosine 5'-O-(3-thiotriphosphate).

Biological signals, 1995
Melatonin receptors were studied in quail livers using the melatonin agonist 2-[125I]iodomelatonin ([125I]MEL) as the radioligand. The specific binding of [125I]MEL to membrane preparations of liver was rapid, stable, saturable, reversible and of high affinity.
Q, Wan, S F, Pang
openaire   +1 more source

Rapid binding of guanosine 5'-O-(3-thiotriphosphate) to an apparent complex of beta-adrenergic receptor and the GTP-binding regulatory protein Gs.

Biochemistry, 1988
When reconstituted phospholipid vesicles that contain purified beta-adrenergic receptors and the GTP-binding regulatory protein Gs were preincubated with agonist before the addition of guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S), the typical receptor-stimulated GTP gamma S binding reaction was preceded by an even more rapid burst of GTP gamma S ...
D C, May, E M, Ross
openaire   +1 more source

Role of G-protein availability in differential signaling by alpha 2-adrenoceptors 1 1Abbreviations: α2-AR, α2-adrenergic receptor; AC, adenylyl cyclase; GTPγS, guanosine 5′-O-(3-thiotriphosphate); IBMX, 3-isobutyl-1-methyl-xanthine; UK14,304, 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)-6-quinoxalinamine.

Biochemical Pharmacology, 2001
Johnny Nasman, Jyrki P Kukkonen, Sylwia Ammoun, Karl E.O Akerman   +3 more
openaire   +1 more source