Results 11 to 20 of about 37,457,458 (124)
Excited State Dynamics of 7-Deazaguanosine and Guanosine 5’ Monophosphate [PDF]
Minor structural modifications to the DNA and RNA nucleobases have a significant effect on their excited state dynamics and electronic relaxation pathways.
Sarah E., Krul +3 more
core +1 more source
Guanosine 5'-O-(3-thiotriphosphate) inhibits capping of reovirus mRNA.
RNA synthesized by reovirus cores was not capped or methylated when GTP was replaced by guanosine 5'-O-(3-thiotriphosphate) [gamma-S]GTP as a reaction substrate. Full length transcripts were synthesized in the presence of [gamma-S]GTP which indicated that capping could be dissociated from the process of transcription.
A E, Reeve, A J, Shatkin, R C, Huang
openaire +2 more sources
Guanosine 5'-O-(3-thiotriphosphate), a potent nucleotide inhibitor of microtubule assembly.
Guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) and the two diastereoisomers of guanosine 5'-O-(2-thiotriphosphate) (GTP beta S) were prepared enzymatically, and their interactions with tubulin and microtubule-associated proteins (MAPs) in 0.1 M 2-(N-morpholino)ethanesulfonate, 0.5 mM MgCl2 were examined.
E, Hamel, C M, Lin
openaire +2 more sources
Muscarinic acetylcholine receptor‐stimulated binding of guanosine 5′‐O‐(3‐thiotriphosphate) to guanine‐nucleotide‐binding proteins in cardiac membranes [PDF]
Receptor‐regulated binding of the labeled GTP analog, guanosine 5′‐O‐(3‐thiotriphosphate) ([35S]GTP[S]), to guanine‐nucleotide‐binding proteins (G‐proteins) was studied in porcine atrial membranes enriched in muscarinic acetylcholine (mACh) receptors. Binding of [35S]GTP[S] to the membranes was not or only slightly affected by the cholinergic agonist ...
G, Hilf, P, Gierschik, K H, Jakobs
openaire +2 more sources
Are guanine nucleotide-binding proteins involved in regulation of thylakoid protein kinase activity? [PDF]
The slow ATP-induced decrease in chlorophyll fluorescence associated with the phosphorylation of LHC II seen in spinach thylakoids was inhibited by GTP and its non-hydrolysable analogues β, γ-imidoguanosine 5′-triphosphate and guanosine 5′-O-(3 ...
Paul A. Millner, Millner, Paul A.
core +1 more source
L'ajout de guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) à des fibroblastes pulmonaires intacts de hamster chinois (CCL39) dépolarisés par des concentrations élevées de K+ entraîne l'activation de la phospholipase C spécifique du phosphoinositide (PLC) (à des concentrations de GTP gamma S supérieures à 0,1 mM), l'inhibition de l'adénylate cyclase ...
S Paris, Jacques Pouysségur
openaire +2 more sources
Effects of guanosine 5'-O-(3-thiotriphosphate) (GTP gamma S) and cations on 2-[125I]iodomelatonin binding were investigated in membrane preparations of the chicken spinal cord. At concentrations of 10 and 50 mumol/l, GTP gamma S dose-dependently increased (p < 0.05) the equilibrium dissociation constant (Kd) and depressed (p < 0.05) the maximum number ...
Q, Wan +4 more
openaire +2 more sources
Guanosine nucleotide-dependent activation of the amiloride-blockable Na+ channel
Effects of guanosine nucleotides on the epithelial Na+ channel were studied in apical membrane vesicles derived from the toad bladder epithelium. Trapping 10 microM guanosine-5'-O-(thiotriphosphate) (GTP gamma S) in vesicles evoked two- to fourfold ...
H. Garty +3 more
core +1 more source
An Effector of Hemoglobin Structure: The Guanosine 3', 5'-Triphosphate [PDF]
The effect of guanosine 3', 5'-triphosphate (GTP) on the hemoglobin structure was studied by UV-visible, fluorescence and circular dichroism (CD) spectroscopies, and cyclic voltammetry.
Arefi, Mohammad Reza +11 more
core +1 more source
The very useful radiolabeled ATP analog, adenosine 5-O-(3-[35S] thiotriphosphate) or [35S] ATPgammaS, has been prepared by a technique based on the thiophosphorylation of ADP that results in much higher yields of [35S] ATPgammaS than does a thiophosphate
Cassidy, P S, Kerrick, W G
core +2 more sources

